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capn3a calpain 3a, (p94) [ Oreochromis aureus ]

Gene ID: 116318066, updated on 18-Jun-2024

Summary

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Gene symbol
capn3a
Gene description
calpain 3a, (p94)
See related
Ensembl:ENSOABG00000003292
Gene type
protein coding
RefSeq status
MODEL
Organism
Oreochromis aureus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini; Oreochromis
Orthologs
human zebrafish all
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Genomic context

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See capn3a in Genome Data Viewer
Location:
chromosome: 19
Exon count:
21
Annotation release Status Assembly LG Location
101 current ZZ_aureus (GCF_013358895.1) 19 NC_052960.1 (9766106..9778949)
100 previous assembly ASM587006v1 (GCF_005870065.1) Unplaced Scaffold NW_022249552.1 (2326395..2338723, complement)

Linkage Group 19 - NC_052960.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 87A Neighboring gene glucosidase, alpha; neutral C Neighboring gene zinc finger protein 106a Neighboring gene proton activated chloride channel 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oreochromis aureus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ZZ_aureus Primary Assembly

Genomic

  1. NC_052960.1 Reference ZZ_aureus Primary Assembly

    Range
    9766106..9778949
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039603627.1 → XP_039459561.1  calpain-3 isoform X1

    UniProtKB/TrEMBL
    A0A668S2S4
    Conserved Domains (4) summary
    smart00230
    Location:37 → 361
    CysPc; Calpain-like thiol protease family
    cd00214
    Location:363 → 520
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    cd15897
    Location:545 → 573
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:545 → 715
    EFh_PEF; The penta-EF hand (PEF) family

  2. XM_031736982.2 → XP_031592842.1  calpain-3 isoform X2

    UniProtKB/TrEMBL
    A0A668S2S4
    Related
    ENSOABP00000005859.1, ENSOABT00000006071.2
    Conserved Domains (4) summary
    cd15897
    Location:545 → 573
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:545 → 712
    EFh_PEF; The penta-EF hand (PEF) family
    pfam00648
    Location:51 → 351
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:372 → 515
    Calpain_III; Calpain large subunit, domain III
Nucleotide Protein Strain
Heading Accession and Version

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