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pleca plectin a [ Oreochromis aureus ]

Gene ID: 116315285, updated on 18-Jun-2024

Summary

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Gene symbol
pleca
Gene description
plectin a
See related
Ensembl:ENSOABG00000005968
Gene type
protein coding
RefSeq status
MODEL
Organism
Oreochromis aureus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini; Oreochromis
Orthologs
zebrafish all
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Genomic context

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See pleca in Genome Data Viewer
Location:
chromosome: 22
Exon count:
41
Annotation release Status Assembly LG Location
101 current ZZ_aureus (GCF_013358895.1) 22 NC_052962.1 (28402490..28507776, complement)
100 previous assembly ASM587006v1 (GCF_005870065.1) Unplaced Scaffold NW_022245371.1 (615870..655912)

Linkage Group 22 - NC_052962.1Genomic Context describing neighboring genes Neighboring gene F-box and leucine-rich repeat protein 6 Neighboring gene epiplakin 1 Neighboring gene doublesex and mab-3 related transcription factor 1-like Neighboring gene eukaryotic translation initiation factor 3, subunit E, b Neighboring gene transmembrane protein 74

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ankyrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural constituent of muscle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in hemidesmosome assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intermediate filament cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in wound healing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in hemidesmosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
plectin a

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oreochromis aureus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ZZ_aureus Primary Assembly

Genomic

  1. NC_052962.1 Reference ZZ_aureus Primary Assembly

    Range
    28402490..28507776 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039606038.1 → XP_039461972.1  plectin a isoform X1

    UniProtKB/TrEMBL
    A0A668UZN1
    Related
    ENSOABP00000044079.2, ENSOABT00000045240.2
    Conserved Domains (7) summary
    PTZ00121
    Location:1537 → 2465
    PTZ00121; MAEBL; Provisional
    smart00250
    Location:4360 → 4397
    PLEC; Plectin repeat
    COG1196
    Location:1075 → 1843
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5069
    Location:67 → 289
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:663 → 853
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam17380
    Location:2307 → 2700
    DUF5401; Family of unknown function (DUF5401)
    cl17036
    Location:855 → 900
    SH3; Src Homology 3 domain superfamily

  2. XM_039606042.1 → XP_039461976.1  plectin a isoform X6

    UniProtKB/TrEMBL
    A0A668V0L5
    Related
    ENSOABP00000044297.2, ENSOABT00000045462.2
    Conserved Domains (7) summary
    PTZ00121
    Location:1500 → 2428
    PTZ00121; MAEBL; Provisional
    smart00250
    Location:4323 → 4360
    PLEC; Plectin repeat
    COG1196
    Location:1038 → 1806
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5069
    Location:35 → 252
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:626 → 816
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam17380
    Location:2270 → 2663
    DUF5401; Family of unknown function (DUF5401)
    cl17036
    Location:818 → 863
    SH3; Src Homology 3 domain superfamily

  3. XM_039606043.1 → XP_039461977.1  plectin a isoform X7

    UniProtKB/TrEMBL
    A0A668V0L5
    Related
    ENSOABP00000044357.2, ENSOABT00000045522.2
    Conserved Domains (7) summary
    PTZ00121
    Location:1485 → 2413
    PTZ00121; MAEBL; Provisional
    smart00250
    Location:4308 → 4345
    PLEC; Plectin repeat
    COG1196
    Location:1023 → 1791
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5069
    Location:20 → 237
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:611 → 801
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam17380
    Location:2255 → 2648
    DUF5401; Family of unknown function (DUF5401)
    cl17036
    Location:803 → 848
    SH3; Src Homology 3 domain superfamily

  4. XM_039606044.1 → XP_039461978.1  plectin a isoform X8

    UniProtKB/TrEMBL
    A0A668V0I3
    Related
    ENSOABP00000044295.2, ENSOABT00000045459.2
    Conserved Domains (7) summary
    PTZ00121
    Location:1483 → 2411
    PTZ00121; MAEBL; Provisional
    smart00250
    Location:4306 → 4343
    PLEC; Plectin repeat
    COG1196
    Location:1021 → 1789
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5069
    Location:18 → 235
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:609 → 799
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam17380
    Location:2253 → 2646
    DUF5401; Family of unknown function (DUF5401)
    cl17036
    Location:801 → 846
    SH3; Src Homology 3 domain superfamily

  5. XM_039606040.1 → XP_039461974.1  plectin a isoform X4

    UniProtKB/TrEMBL
    A0A668V0L5
    Related
    ENSOABP00000044084.2, ENSOABT00000045245.2
    Conserved Domains (7) summary
    PTZ00121
    Location:1504 → 2432
    PTZ00121; MAEBL; Provisional
    smart00250
    Location:4327 → 4364
    PLEC; Plectin repeat
    COG1196
    Location:1042 → 1810
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5069
    Location:39 → 256
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:630 → 820
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam17380
    Location:2274 → 2667
    DUF5401; Family of unknown function (DUF5401)
    cl17036
    Location:822 → 867
    SH3; Src Homology 3 domain superfamily

  6. XM_039606039.1 → XP_039461973.1  plectin a isoform X2

    UniProtKB/TrEMBL
    A0A668V0I3
    Related
    ENSOABP00000043860.2, ENSOABT00000045018.2
    Conserved Domains (7) summary
    PTZ00121
    Location:1520 → 2448
    PTZ00121; MAEBL; Provisional
    smart00250
    Location:4343 → 4380
    PLEC; Plectin repeat
    COG1196
    Location:1058 → 1826
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5069
    Location:50 → 272
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:646 → 836
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam17380
    Location:2290 → 2683
    DUF5401; Family of unknown function (DUF5401)
    cl17036
    Location:838 → 883
    SH3; Src Homology 3 domain superfamily

  7. XM_039606041.1 → XP_039461975.1  plectin a isoform X5

    UniProtKB/TrEMBL
    A0A668V0I3
    Conserved Domains (7) summary
    PTZ00121
    Location:1501 → 2429
    PTZ00121; MAEBL; Provisional
    smart00250
    Location:4324 → 4361
    PLEC; Plectin repeat
    COG1196
    Location:1039 → 1807
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5069
    Location:43 → 260
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:634 → 824
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam17380
    Location:2271 → 2664
    DUF5401; Family of unknown function (DUF5401)
    cl17036
    Location:826 → 871
    SH3; Src Homology 3 domain superfamily

  8. XM_031733553.2 → XP_031589413.1  plectin a isoform X3

    UniProtKB/TrEMBL
    A0A668V0I3
    Related
    ENSOABP00000044359.2, ENSOABT00000045524.2
    Conserved Domains (9) summary
    PTZ00121
    Location:1508 → 2436
    PTZ00121; MAEBL; Provisional
    smart00250
    Location:3117 → 3153
    PLEC; Plectin repeat
    COG1196
    Location:1046 → 1814
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5069
    Location:43 → 260
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:634 → 824
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4332 → 4372
    Plectin; Plectin repeat
    pfam17380
    Location:2278 → 2671
    DUF5401; Family of unknown function (DUF5401)
    pfam17902
    Location:810 → 876
    SH3_10; SH3 domain
    pfam18373
    Location:911 → 988
    Spectrin_like; Spectrin like domain
Nucleotide Protein Strain
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