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pleca plectin a [ Sander lucioperca (pikeperch) ]

Gene ID: 116047150, updated on 21-Aug-2024

Summary

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Gene symbol
pleca
Gene description
plectin a
See related
EnsemblRapid:ENSSLUG00000023941
Gene type
protein coding
RefSeq status
MODEL
Organism
Sander lucioperca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Percoidei; Percidae; Luciopercinae; Sander
Also known as
plec
Orthologs
zebrafish all
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Genomic context

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See pleca in Genome Data Viewer
Location:
chromosome: 14
Exon count:
47
Annotation release Status Assembly Chr Location
101 current SLUC_FBN_1.2 (GCF_008315115.2) 14 NC_050186.1 (20125516..20236885, complement)
100 previous assembly SLUC_FBN_1 (GCF_008315115.1) Unplaced Scaffold NW_022172743.1 (2198471..2303370)

Chromosome 14 - NC_050186.1Genomic Context describing neighboring genes Neighboring gene epiplakin 1 Neighboring gene doublesex- and mab-3-related transcription factor B1-like Neighboring gene eukaryotic translation initiation factor 3, subunit E, b Neighboring gene transmembrane protein 74

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ankyrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural constituent of muscle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in hemidesmosome assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intermediate filament cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in wound healing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in hemidesmosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
plectin a
Names
plectin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sander lucioperca Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference SLUC_FBN_1.2 Primary Assembly

Genomic

  1. NC_050186.1 Reference SLUC_FBN_1.2 Primary Assembly

    Range
    20125516..20236885 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035991335.1 → XP_035847228.1  plectin a isoform X3

    UniProtKB/TrEMBL
    A0A8D0AL97
    Conserved Domains (11) summary
    PTZ00121
    Location:1962 → 2754
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:702 → 796
    SPEC; Spectrin repeats
    smart00250
    Location:4449 → 4482
    PLEC; Plectin repeat
    COG0419
    Location:1167 → 1823
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    PRK00409
    Location:2685 → 2872
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:797 → 987
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4214 → 4253
    Plectin; Plectin repeat
    pfam17902
    Location:973 → 1039
    SH3_10; SH3 domain
    pfam18373
    Location:1074 → 1151
    Spectrin_like; Spectrin like domain
    cd21188
    Location:198 → 319
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:332 → 437
    CH_SF; calponin homology (CH) domain superfamily

  2. XM_035991333.1 → XP_035847226.1  plectin a isoform X1

    UniProtKB/TrEMBL
    A0A8D0AS28
    Conserved Domains (11) summary
    PTZ00121
    Location:1969 → 2761
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:702 → 796
    SPEC; Spectrin repeats
    smart00250
    Location:4456 → 4489
    PLEC; Plectin repeat
    COG0419
    Location:1174 → 1830
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    PRK00409
    Location:2692 → 2879
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:797 → 987
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4221 → 4260
    Plectin; Plectin repeat
    pfam17902
    Location:973 → 1039
    SH3_10; SH3 domain
    pfam18373
    Location:1074 → 1151
    Spectrin_like; Spectrin like domain
    cd21188
    Location:198 → 319
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:332 → 437
    CH_SF; calponin homology (CH) domain superfamily

  3. XM_035991339.1 → XP_035847232.1  plectin a isoform X6

    UniProtKB/TrEMBL
    A0A8D0AL97
    Conserved Domains (11) summary
    PTZ00121
    Location:1945 → 2737
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:685 → 779
    SPEC; Spectrin repeats
    smart00250
    Location:4432 → 4465
    PLEC; Plectin repeat
    COG0419
    Location:1150 → 1806
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    PRK00409
    Location:2668 → 2855
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:780 → 970
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4197 → 4236
    Plectin; Plectin repeat
    pfam17902
    Location:956 → 1022
    SH3_10; SH3 domain
    pfam18373
    Location:1057 → 1134
    Spectrin_like; Spectrin like domain
    cd21188
    Location:198 → 302
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:315 → 420
    CH_SF; calponin homology (CH) domain superfamily

  4. XM_035991338.1 → XP_035847231.1  plectin a isoform X5

    UniProtKB/TrEMBL
    A0A8D0AL97
    Conserved Domains (11) summary
    PTZ00121
    Location:1952 → 2744
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:685 → 779
    SPEC; Spectrin repeats
    smart00250
    Location:4439 → 4472
    PLEC; Plectin repeat
    COG0419
    Location:1157 → 1813
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    PRK00409
    Location:2675 → 2862
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:780 → 970
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4204 → 4243
    Plectin; Plectin repeat
    pfam17902
    Location:956 → 1022
    SH3_10; SH3 domain
    pfam18373
    Location:1057 → 1134
    Spectrin_like; Spectrin like domain
    cd21188
    Location:198 → 302
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:315 → 420
    CH_SF; calponin homology (CH) domain superfamily

  5. XM_035991337.1 → XP_035847230.1  plectin a isoform X4

    UniProtKB/TrEMBL
    A0A8D0AL97
    Conserved Domains (11) summary
    PTZ00121
    Location:1957 → 2749
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:690 → 784
    SPEC; Spectrin repeats
    smart00250
    Location:4444 → 4477
    PLEC; Plectin repeat
    COG0419
    Location:1162 → 1818
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    PRK00409
    Location:2680 → 2867
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:785 → 975
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4209 → 4248
    Plectin; Plectin repeat
    pfam17902
    Location:961 → 1027
    SH3_10; SH3 domain
    pfam18373
    Location:1062 → 1139
    Spectrin_like; Spectrin like domain
    cd21188
    Location:198 → 307
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:320 → 425
    CH_SF; calponin homology (CH) domain superfamily

  6. XM_035991334.1 → XP_035847227.1  plectin a isoform X2

    UniProtKB/TrEMBL
    A0A8D0AS28
    Conserved Domains (11) summary
    PTZ00121
    Location:1964 → 2756
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:697 → 791
    SPEC; Spectrin repeats
    smart00250
    Location:4451 → 4484
    PLEC; Plectin repeat
    COG0419
    Location:1169 → 1825
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    PRK00409
    Location:2687 → 2874
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:792 → 982
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4216 → 4255
    Plectin; Plectin repeat
    pfam17902
    Location:968 → 1034
    SH3_10; SH3 domain
    pfam18373
    Location:1069 → 1146
    Spectrin_like; Spectrin like domain
    cd21188
    Location:198 → 314
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:327 → 432
    CH_SF; calponin homology (CH) domain superfamily

  7. XM_031295695.2 → XP_031151555.1  plectin a isoform X7

    UniProtKB/TrEMBL
    A0A8D0AS28
    Conserved Domains (10) summary
    PTZ00121
    Location:1845 → 2637
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:578 → 672
    SPEC; Spectrin repeats
    smart00250
    Location:4332 → 4365
    PLEC; Plectin repeat
    COG0419
    Location:1050 → 1706
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG5069
    Location:70 → 309
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    PRK00409
    Location:2568 → 2755
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:673 → 863
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4097 → 4136
    Plectin; Plectin repeat
    pfam17902
    Location:849 → 915
    SH3_10; SH3 domain
    pfam18373
    Location:950 → 1027
    Spectrin_like; Spectrin like domain

  8. XM_035991344.1 → XP_035847237.1  plectin a isoform X24

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Related
    ENSSLUP00000056591.2, ENSSLUT00000058244.2
    Conserved Domains (11) summary
    PTZ00121
    Location:1788 → 2580
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:521 → 615
    SPEC; Spectrin repeats
    smart00250
    Location:4275 → 4308
    PLEC; Plectin repeat
    COG0419
    Location:993 → 1649
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    PRK00409
    Location:2511 → 2698
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:616 → 806
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4040 → 4079
    Plectin; Plectin repeat
    pfam17902
    Location:792 → 858
    SH3_10; SH3 domain
    pfam18373
    Location:893 → 970
    Spectrin_like; Spectrin like domain
    cd21188
    Location:34 → 138
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:151 → 256
    CH_SF; calponin homology (CH) domain superfamily

  9. XM_031295707.2 → XP_031151567.1  plectin a isoform X17

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Conserved Domains (10) summary
    PTZ00121
    Location:1800 → 2592
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:533 → 627
    SPEC; Spectrin repeats
    smart00250
    Location:4287 → 4320
    PLEC; Plectin repeat
    COG0419
    Location:1005 → 1661
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG5069
    Location:35 → 264
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    PRK00409
    Location:2523 → 2710
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:628 → 818
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4052 → 4091
    Plectin; Plectin repeat
    pfam17902
    Location:804 → 870
    SH3_10; SH3 domain
    pfam18373
    Location:905 → 982
    Spectrin_like; Spectrin like domain

  10. XM_035991342.1 → XP_035847235.1  plectin a isoform X20

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Conserved Domains (11) summary
    PTZ00121
    Location:1793 → 2585
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:526 → 620
    SPEC; Spectrin repeats
    smart00250
    Location:4280 → 4313
    PLEC; Plectin repeat
    COG0419
    Location:998 → 1654
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    PRK00409
    Location:2516 → 2703
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:621 → 811
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4045 → 4084
    Plectin; Plectin repeat
    pfam17902
    Location:797 → 863
    SH3_10; SH3 domain
    pfam18373
    Location:898 → 975
    Spectrin_like; Spectrin like domain
    cd21188
    Location:34 → 143
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:156 → 261
    CH_SF; calponin homology (CH) domain superfamily

  11. XM_031295704.2 → XP_031151564.1  plectin a isoform X14

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Conserved Domains (10) summary
    PTZ00121
    Location:1805 → 2597
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:538 → 632
    SPEC; Spectrin repeats
    smart00250
    Location:4292 → 4325
    PLEC; Plectin repeat
    COG0419
    Location:1010 → 1666
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG5069
    Location:35 → 269
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    PRK00409
    Location:2528 → 2715
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:633 → 823
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4057 → 4096
    Plectin; Plectin repeat
    pfam17902
    Location:809 → 875
    SH3_10; SH3 domain
    pfam18373
    Location:910 → 987
    Spectrin_like; Spectrin like domain

  12. XM_031295713.2 → XP_031151573.1  plectin a isoform X26

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Conserved Domains (10) summary
    PTZ00121
    Location:1785 → 2577
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:518 → 612
    SPEC; Spectrin repeats
    smart00250
    Location:4272 → 4305
    PLEC; Plectin repeat
    COG0419
    Location:990 → 1646
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG5069
    Location:20 → 249
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    PRK00409
    Location:2508 → 2695
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:613 → 803
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4037 → 4076
    Plectin; Plectin repeat
    pfam17902
    Location:789 → 855
    SH3_10; SH3 domain
    pfam18373
    Location:890 → 967
    Spectrin_like; Spectrin like domain

  13. XM_031295710.2 → XP_031151570.1  plectin a isoform X22

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Conserved Domains (10) summary
    PTZ00121
    Location:1790 → 2582
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:523 → 617
    SPEC; Spectrin repeats
    smart00250
    Location:4277 → 4310
    PLEC; Plectin repeat
    COG0419
    Location:995 → 1651
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG5069
    Location:20 → 254
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    PRK00409
    Location:2513 → 2700
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:618 → 808
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4042 → 4081
    Plectin; Plectin repeat
    pfam17902
    Location:794 → 860
    SH3_10; SH3 domain
    pfam18373
    Location:895 → 972
    Spectrin_like; Spectrin like domain

  14. XM_035991345.1 → XP_035847238.1  plectin a isoform X28

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Related
    ENSSLUP00000056622.2, ENSSLUT00000058275.2
    Conserved Domains (11) summary
    PTZ00121
    Location:1773 → 2565
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:506 → 600
    SPEC; Spectrin repeats
    smart00250
    Location:4260 → 4293
    PLEC; Plectin repeat
    COG0419
    Location:978 → 1634
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    PRK00409
    Location:2496 → 2683
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:601 → 791
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4025 → 4064
    Plectin; Plectin repeat
    pfam17902
    Location:777 → 843
    SH3_10; SH3 domain
    pfam18373
    Location:878 → 955
    Spectrin_like; Spectrin like domain
    cd21188
    Location:19 → 123
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:136 → 241
    CH_SF; calponin homology (CH) domain superfamily

  15. XM_035991347.1 → XP_035847240.1  plectin a isoform X29

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Related
    ENSSLUP00000056599.2, ENSSLUT00000058252.2
    Conserved Domains (11) summary
    PTZ00121
    Location:1771 → 2563
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:504 → 598
    SPEC; Spectrin repeats
    smart00250
    Location:4258 → 4291
    PLEC; Plectin repeat
    COG0419
    Location:976 → 1632
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    PRK00409
    Location:2494 → 2681
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:599 → 789
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4023 → 4062
    Plectin; Plectin repeat
    pfam17902
    Location:775 → 841
    SH3_10; SH3 domain
    pfam18373
    Location:876 → 953
    Spectrin_like; Spectrin like domain
    cd21188
    Location:17 → 121
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:134 → 239
    CH_SF; calponin homology (CH) domain superfamily

  16. XM_031295715.2 → XP_031151575.1  plectin a isoform X27

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Related
    ENSSLUP00000056581.2, ENSSLUT00000058234.2
    Conserved Domains (10) summary
    PTZ00121
    Location:1783 → 2575
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:516 → 610
    SPEC; Spectrin repeats
    smart00250
    Location:4270 → 4303
    PLEC; Plectin repeat
    COG0419
    Location:988 → 1644
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG5069
    Location:18 → 247
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    PRK00409
    Location:2506 → 2693
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:611 → 801
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4035 → 4074
    Plectin; Plectin repeat
    pfam17902
    Location:787 → 853
    SH3_10; SH3 domain
    pfam18373
    Location:888 → 965
    Spectrin_like; Spectrin like domain

  17. XM_031295712.2 → XP_031151572.1  plectin a isoform X25

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Conserved Domains (10) summary
    PTZ00121
    Location:1788 → 2580
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:521 → 615
    SPEC; Spectrin repeats
    smart00250
    Location:4275 → 4308
    PLEC; Plectin repeat
    COG0419
    Location:993 → 1649
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG5069
    Location:18 → 252
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    PRK00409
    Location:2511 → 2698
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:616 → 806
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4040 → 4079
    Plectin; Plectin repeat
    pfam17902
    Location:792 → 858
    SH3_10; SH3 domain
    pfam18373
    Location:893 → 970
    Spectrin_like; Spectrin like domain

  18. XM_031295705.2 → XP_031151565.1  plectin a isoform X15

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Conserved Domains (10) summary
    PTZ00121
    Location:1804 → 2596
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:537 → 631
    SPEC; Spectrin repeats
    smart00250
    Location:4291 → 4324
    PLEC; Plectin repeat
    COG0419
    Location:1009 → 1665
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG5069
    Location:39 → 268
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    PRK00409
    Location:2527 → 2714
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:632 → 822
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4056 → 4095
    Plectin; Plectin repeat
    pfam17902
    Location:808 → 874
    SH3_10; SH3 domain
    pfam18373
    Location:909 → 986
    Spectrin_like; Spectrin like domain

  19. XM_035991341.1 → XP_035847234.1  plectin a isoform X18

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Conserved Domains (11) summary
    PTZ00121
    Location:1797 → 2589
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:530 → 624
    SPEC; Spectrin repeats
    smart00250
    Location:4284 → 4317
    PLEC; Plectin repeat
    COG0419
    Location:1002 → 1658
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    PRK00409
    Location:2520 → 2707
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:625 → 815
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4049 → 4088
    Plectin; Plectin repeat
    pfam17902
    Location:801 → 867
    SH3_10; SH3 domain
    pfam18373
    Location:902 → 979
    Spectrin_like; Spectrin like domain
    cd21188
    Location:38 → 147
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:160 → 265
    CH_SF; calponin homology (CH) domain superfamily

  20. XM_031295701.2 → XP_031151561.1  plectin a isoform X11

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Conserved Domains (10) summary
    PTZ00121
    Location:1809 → 2601
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:542 → 636
    SPEC; Spectrin repeats
    smart00250
    Location:4296 → 4329
    PLEC; Plectin repeat
    COG0419
    Location:1014 → 1670
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG5069
    Location:39 → 273
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    PRK00409
    Location:2532 → 2719
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:637 → 827
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4061 → 4100
    Plectin; Plectin repeat
    pfam17902
    Location:813 → 879
    SH3_10; SH3 domain
    pfam18373
    Location:914 → 991
    Spectrin_like; Spectrin like domain

  21. XM_035991343.1 → XP_035847236.1  plectin a isoform X21

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Related
    ENSSLUP00000056594.2, ENSSLUT00000058247.2
    Conserved Domains (11) summary
    PTZ00121
    Location:1792 → 2584
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:525 → 619
    SPEC; Spectrin repeats
    smart00250
    Location:4279 → 4312
    PLEC; Plectin repeat
    COG0419
    Location:997 → 1653
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    PRK00409
    Location:2515 → 2702
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:620 → 810
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4044 → 4083
    Plectin; Plectin repeat
    pfam17902
    Location:796 → 862
    SH3_10; SH3 domain
    pfam18373
    Location:897 → 974
    Spectrin_like; Spectrin like domain
    cd21188
    Location:38 → 142
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:155 → 260
    CH_SF; calponin homology (CH) domain superfamily

  22. XM_031295706.2 → XP_031151566.1  plectin a isoform X16

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Conserved Domains (10) summary
    PTZ00121
    Location:1801 → 2593
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:541 → 635
    SPEC; Spectrin repeats
    smart00250
    Location:4288 → 4321
    PLEC; Plectin repeat
    COG0419
    Location:1006 → 1662
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG5069
    Location:50 → 272
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    PRK00409
    Location:2524 → 2711
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:636 → 826
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4053 → 4092
    Plectin; Plectin repeat
    pfam17902
    Location:812 → 878
    SH3_10; SH3 domain
    pfam18373
    Location:913 → 990
    Spectrin_like; Spectrin like domain

  23. XM_035991340.1 → XP_035847233.1  plectin a isoform X12

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Related
    ENSSLUP00000056587.2, ENSSLUT00000058240.2
    Conserved Domains (11) summary
    PTZ00121
    Location:1808 → 2600
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:541 → 635
    SPEC; Spectrin repeats
    smart00250
    Location:4295 → 4328
    PLEC; Plectin repeat
    COG0419
    Location:1013 → 1669
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    PRK00409
    Location:2531 → 2718
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:636 → 826
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4060 → 4099
    Plectin; Plectin repeat
    pfam17902
    Location:812 → 878
    SH3_10; SH3 domain
    pfam18373
    Location:913 → 990
    Spectrin_like; Spectrin like domain
    cd21188
    Location:54 → 158
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:171 → 276
    CH_SF; calponin homology (CH) domain superfamily

  24. XM_031295699.2 → XP_031151559.1  plectin a isoform X9

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Conserved Domains (10) summary
    PTZ00121
    Location:1820 → 2612
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:553 → 647
    SPEC; Spectrin repeats
    smart00250
    Location:4307 → 4340
    PLEC; Plectin repeat
    COG0419
    Location:1025 → 1681
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG5069
    Location:50 → 284
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    PRK00409
    Location:2543 → 2730
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:648 → 838
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4072 → 4111
    Plectin; Plectin repeat
    pfam17902
    Location:824 → 890
    SH3_10; SH3 domain
    pfam18373
    Location:925 → 1002
    Spectrin_like; Spectrin like domain

  25. XM_031295697.2 → XP_031151557.1  plectin a isoform X8

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Conserved Domains (10) summary
    PTZ00121
    Location:1825 → 2617
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:558 → 652
    SPEC; Spectrin repeats
    smart00250
    Location:4312 → 4345
    PLEC; Plectin repeat
    COG0419
    Location:1030 → 1686
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG5069
    Location:50 → 289
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    PRK00409
    Location:2548 → 2735
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:653 → 843
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4077 → 4116
    Plectin; Plectin repeat
    pfam17902
    Location:829 → 895
    SH3_10; SH3 domain
    pfam18373
    Location:930 → 1007
    Spectrin_like; Spectrin like domain

  26. XM_031295709.2 → XP_031151569.1  plectin a isoform X19

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Related
    ENSSLUP00000056462.2, ENSSLUT00000058113.2
    Conserved Domains (10) summary
    PTZ00121
    Location:1796 → 2588
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:529 → 623
    SPEC; Spectrin repeats
    smart00250
    Location:4283 → 4316
    PLEC; Plectin repeat
    COG0419
    Location:1001 → 1657
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG5069
    Location:43 → 260
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    PRK00409
    Location:2519 → 2706
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:624 → 814
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4048 → 4087
    Plectin; Plectin repeat
    pfam17902
    Location:800 → 866
    SH3_10; SH3 domain
    pfam18373
    Location:901 → 978
    Spectrin_like; Spectrin like domain

  27. XM_031295703.2 → XP_031151563.1  plectin a isoform X13

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Conserved Domains (10) summary
    PTZ00121
    Location:1808 → 2600
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:541 → 635
    SPEC; Spectrin repeats
    smart00250
    Location:4295 → 4328
    PLEC; Plectin repeat
    COG0419
    Location:1013 → 1669
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG5069
    Location:43 → 272
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    PRK00409
    Location:2531 → 2718
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:636 → 826
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4060 → 4099
    Plectin; Plectin repeat
    pfam17902
    Location:812 → 878
    SH3_10; SH3 domain
    pfam18373
    Location:913 → 990
    Spectrin_like; Spectrin like domain

  28. XM_031295700.2 → XP_031151560.1  plectin a isoform X10

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Conserved Domains (10) summary
    PTZ00121
    Location:1813 → 2605
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:546 → 640
    SPEC; Spectrin repeats
    smart00250
    Location:4300 → 4333
    PLEC; Plectin repeat
    COG0419
    Location:1018 → 1674
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG5069
    Location:43 → 277
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    PRK00409
    Location:2536 → 2723
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:641 → 831
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4065 → 4104
    Plectin; Plectin repeat
    pfam17902
    Location:817 → 883
    SH3_10; SH3 domain
    pfam18373
    Location:918 → 995
    Spectrin_like; Spectrin like domain

  29. XM_031295711.1 → XP_031151571.1  plectin a isoform X23

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Related
    ENSSLUP00000056585.2, ENSSLUT00000058238.2
    Conserved Domains (10) summary
    PTZ00121
    Location:1789 → 2581
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:529 → 623
    SPEC; Spectrin repeats
    smart00250
    Location:4276 → 4309
    PLEC; Plectin repeat
    COG0419
    Location:994 → 1650
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG5069
    Location:43 → 260
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    PRK00409
    Location:2512 → 2699
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:624 → 814
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4041 → 4080
    Plectin; Plectin repeat
    pfam17902
    Location:800 → 866
    SH3_10; SH3 domain
    pfam18373
    Location:901 → 978
    Spectrin_like; Spectrin like domain

  30. XM_035991348.1 → XP_035847241.1  plectin a isoform X30

    UniProtKB/TrEMBL
    A0A8D0AMS7
    Conserved Domains (10) summary
    PTZ00121
    Location:1589 → 2381
    PTZ00121; MAEBL; Provisional
    smart00150
    Location:322 → 416
    SPEC; Spectrin repeats
    smart00250
    Location:4076 → 4109
    PLEC; Plectin repeat
    COG0419
    Location:794 → 1450
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    PRK00409
    Location:2312 → 2499
    PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    cd00176
    Location:417 → 607
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:3841 → 3880
    Plectin; Plectin repeat
    pfam17902
    Location:593 → 659
    SH3_10; SH3 domain
    pfam18373
    Location:694 → 771
    Spectrin_like; Spectrin like domain
    cl00030
    Location:1 → 57
    CH_SF; calponin homology (CH) domain superfamily
Nucleotide Protein
Heading Accession and Version

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