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tjp2a tight junction protein 2a (zona occludens 2) [ Sander lucioperca (pikeperch) ]

Gene ID: 116034727, updated on 21-Aug-2024

Summary

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Gene symbol
tjp2a
Gene description
tight junction protein 2a (zona occludens 2)
See related
EnsemblRapid:ENSSLUG00000022304
Gene type
protein coding
RefSeq status
MODEL
Organism
Sander lucioperca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Percoidei; Percidae; Luciopercinae; Sander
Orthologs
zebrafish all
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Genomic context

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See tjp2a in Genome Data Viewer
Location:
chromosome: 14
Exon count:
30
Annotation release Status Assembly Chr Location
101 current SLUC_FBN_1.2 (GCF_008315115.2) 14 NC_050186.1 (26465072..26510750, complement)
100 previous assembly SLUC_FBN_1 (GCF_008315115.1) Unplaced Scaffold NW_022173134.1 (2764452..2808065, complement)

Chromosome 14 - NC_050186.1Genomic Context describing neighboring genes Neighboring gene MAM domain-containing protein 2-like Neighboring gene amyloid-beta A4 precursor protein-binding family A member 1-like Neighboring gene uncharacterized LOC116034730 Neighboring gene phosphatidylinositol-4-phosphate 5-kinase, type I, beta a Neighboring gene oocyte zinc finger protein XlCOF6-like Neighboring gene uncharacterized LOC116034836

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2a

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sander lucioperca Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference SLUC_FBN_1.2 Primary Assembly

Genomic

  1. NC_050186.1 Reference SLUC_FBN_1.2 Primary Assembly

    Range
    26465072..26510750 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031277433.2 → XP_031133293.1  tight junction protein ZO-2a isoform X3

    UniProtKB/TrEMBL
    A0A8D0AII0
    Conserved Domains (4) summary
    smart00072
    Location:809 → 987
    GuKc; Guanylate kinase homologues
    cd00992
    Location:91 → 176
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:267 → 383
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    cl17036
    Location:709 → 774
    SH3; Src Homology 3 domain superfamily

  2. XM_031277432.2 → XP_031133292.1  tight junction protein ZO-2a isoform X2

    UniProtKB/TrEMBL
    A0A8D0AII0
    Related
    ENSSLUP00000064203.1, ENSSLUT00000069904.1
    Conserved Domains (4) summary
    smart00072
    Location:809 → 987
    GuKc; Guanylate kinase homologues
    cd00992
    Location:91 → 176
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:267 → 383
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    cl17036
    Location:709 → 774
    SH3; Src Homology 3 domain superfamily

  3. XM_031277431.2 → XP_031133291.1  tight junction protein ZO-2a isoform X1

    UniProtKB/TrEMBL
    A0A8D0AII0
    Conserved Domains (4) summary
    smart00072
    Location:809 → 987
    GuKc; Guanylate kinase homologues
    cd00992
    Location:91 → 176
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:267 → 383
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    cl17036
    Location:709 → 774
    SH3; Src Homology 3 domain superfamily

  4. XM_031277436.2 → XP_031133296.1  tight junction protein ZO-2a isoform X5

    UniProtKB/TrEMBL
    A0A8D0AII0
    Related
    ENSSLUP00000051769.2, ENSSLUT00000053288.2
    Conserved Domains (4) summary
    smart00072
    Location:750 → 928
    GuKc; Guanylate kinase homologues
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:208 → 324
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    cl17036
    Location:650 → 715
    SH3; Src Homology 3 domain superfamily

  5. XM_031277434.2 → XP_031133294.1  tight junction protein ZO-2a isoform X4

    UniProtKB/TrEMBL
    A0A8D0AII0
    Conserved Domains (4) summary
    smart00072
    Location:754 → 932
    GuKc; Guanylate kinase homologues
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:212 → 328
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    cl17036
    Location:654 → 719
    SH3; Src Homology 3 domain superfamily

  6. XM_031277438.2 → XP_031133298.1  tight junction protein ZO-2a isoform X7

    UniProtKB/TrEMBL
    A0A8D0AII0
    Related
    ENSSLUP00000051641.2, ENSSLUT00000053158.2
    Conserved Domains (4) summary
    smart00072
    Location:732 → 910
    GuKc; Guanylate kinase homologues
    cd00992
    Location:14 → 99
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:190 → 306
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    cl17036
    Location:632 → 697
    SH3; Src Homology 3 domain superfamily

  7. XM_031277439.2 → XP_031133299.1  tight junction protein ZO-2a isoform X8

    UniProtKB/TrEMBL
    A0A8D0AII0
    Conserved Domains (4) summary
    smart00072
    Location:727 → 905
    GuKc; Guanylate kinase homologues
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:185 → 301
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    cl17036
    Location:627 → 692
    SH3; Src Homology 3 domain superfamily

  8. XM_035991800.1 → XP_035847693.1  tight junction protein ZO-2a isoform X7

    UniProtKB/TrEMBL
    A0A8D0AII0
    Conserved Domains (4) summary
    smart00072
    Location:732 → 910
    GuKc; Guanylate kinase homologues
    cd00992
    Location:14 → 99
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:190 → 306
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    cl17036
    Location:632 → 697
    SH3; Src Homology 3 domain superfamily

  9. XM_031277437.2 → XP_031133297.1  tight junction protein ZO-2a isoform X6

    UniProtKB/TrEMBL
    A0A8D0AII0
    Related
    ENSSLUP00000051794.2, ENSSLUT00000053314.2
    Conserved Domains (4) summary
    smart00072
    Location:754 → 932
    GuKc; Guanylate kinase homologues
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:212 → 328
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    cl17036
    Location:654 → 719
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein
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