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TIAM1 TIAM Rac1 associated GEF 1 [ Camarhynchus parvulus ]

Gene ID: 115917680, updated on 3-Aug-2024

Summary

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Gene symbol
TIAM1
Gene description
TIAM Rac1 associated GEF 1
See related
Ensembl:ENSCPVG00000004105
Gene type
protein coding
RefSeq status
MODEL
Organism
Camarhynchus parvulus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Thraupidae; Camarhynchus
Orthologs
human mouse all
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Genomic context

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See TIAM1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
28
Annotation release Status Assembly Chr Location
100 current STF_HiC (GCF_901933205.1) 1 NC_044571.1 (114542747..114687577)

Chromosome 1 - NC_044571.1Genomic Context describing neighboring genes Neighboring gene SR-related CTD associated factor 4 Neighboring gene superoxide dismutase 1 Neighboring gene protein LIAT1-like Neighboring gene claudin-8-like Neighboring gene uncharacterized LOC115907703

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_044571.1 Chromosome 1 Reference STF_HiC

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: T-lymphoma invasion and metastasis-inducing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Camarhynchus parvulus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference STF_HiC

Genomic

  1. NC_044571.1 Reference STF_HiC

    Range
    114542747..114687577
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030971910.1 → XP_030827770.1  LOW QUALITY PROTEIN: T-lymphoma invasion and metastasis-inducing protein 1

    UniProtKB/TrEMBL
    A0A8C3MFD1, A0A8U8AX19
    Related
    ENSCPVP00000005574.1, ENSCPVT00000005793.1
    Conserved Domains (6) summary
    smart00325
    Location:1049 → 1238
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd00992
    Location:848 → 930
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd01230
    Location:437 → 563
    PH1_Tiam1_2; T-lymphoma invasion and metastasis 1 and 2 Pleckstrin Homology (PH) domain, N-terminal domain
    cd01255
    Location:1240 → 1411
    PH2_Tiam1_2; T-lymphoma invasion and metastasis 1 and 2 Pleckstrin Homology (PH) domain, C-terminal domain
    pfam02196
    Location:771 → 840
    RBD; Raf-like Ras-binding domain
    pfam18385
    Location:577 → 674
    Tiam_CC_Ex; T-lymphoma invasion and metastasis CC-Ex domain
Nucleotide Protein
Heading Accession and Version

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