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HSPG2 heparan sulfate proteoglycan 2 [ Strigops habroptila (Kakapo) ]

Gene ID: 115617448, updated on 3-Aug-2024

Summary

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Gene symbol
HSPG2
Gene description
heparan sulfate proteoglycan 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Strigops habroptila
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Psittaciformes; Psittacidae; Strigops
Orthologs
human mouse all
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Genomic context

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See HSPG2 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
93
Annotation release Status Assembly Chr Location
101 current bStrHab1.2.pri (GCF_004027225.2) 16 NC_044292.2 (2213281..2256890, complement)
100 previous assembly bStrHab1_v1.p (GCF_004027225.1) 17 NC_044293.1 (2213281..2256890, complement)

Chromosome 16 - NC_044292.2Genomic Context describing neighboring genes Neighboring gene RAP1 GTPase activating protein Neighboring gene ubiquitin specific peptidase 48 Neighboring gene E3 ubiquitin-protein ligase TRIM62 Neighboring gene transmembrane protein 269 Neighboring gene small vasohibin binding protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
basement membrane-specific heparan sulfate proteoglycan core protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Strigops habroptila Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bStrHab1.2.pri

Genomic

  1. NC_044292.2 Reference bStrHab1.2.pri

    Range
    2213281..2256890 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030507927.1 → XP_030363787.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X2

    Conserved Domains (15) summary
    cd05743
    Location:429 → 506
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:1775 → 1860
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00409
    Location:2464 → 2541
    IG; Immunoglobulin
    smart00410
    Location:3110 → 3187
    IG_like; Immunoglobulin like
    cd00054
    Location:3369 → 3401
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1164 → 1213
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3718 → 3876
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:333 → 367
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3665 → 3690
    EGF; EGF-like domain
    pfam00052
    Location:1400 → 1532
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1279 → 1326
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:203 → 239
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:1975 → 2061
    I-set; Immunoglobulin I-set domain
    cl02507
    Location:86 → 199
    SEA; SEA domain
    cl11960
    Location:2929 → 3011
    Ig; Immunoglobulin domain

  2. XM_030507926.1 → XP_030363786.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X1

    Conserved Domains (15) summary
    cd05743
    Location:429 → 506
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:1775 → 1860
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00409
    Location:3401 → 3478
    IG; Immunoglobulin
    smart00410
    Location:2943 → 3025
    IG_like; Immunoglobulin like
    cd00054
    Location:3663 → 3692
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1164 → 1213
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:4009 → 4167
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:333 → 367
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3956 → 3981
    EGF; EGF-like domain
    pfam00052
    Location:1400 → 1532
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1279 → 1326
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:203 → 239
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:1975 → 2061
    I-set; Immunoglobulin I-set domain
    cl02507
    Location:86 → 199
    SEA; SEA domain
    cl11960
    Location:3220 → 3302
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version

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