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AGRN agrin [ Strigops habroptila (Kakapo) ]

Gene ID: 115617376, updated on 3-Aug-2024

Summary

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Gene symbol
AGRN
Gene description
agrin
Gene type
protein coding
RefSeq status
MODEL
Organism
Strigops habroptila
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Psittaciformes; Psittacidae; Strigops
Orthologs
human mouse all
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Genomic context

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See AGRN in Genome Data Viewer
Location:
chromosome: 16
Exon count:
40
Annotation release Status Assembly Chr Location
101 current bStrHab1.2.pri (GCF_004027225.2) 16 NC_044292.2 (5336104..5445747)
100 previous assembly bStrHab1_v1.p (GCF_004027225.1) 17 NC_044293.1 (5336104..5445747)

Chromosome 16 - NC_044292.2Genomic Context describing neighboring genes Neighboring gene PPARGC1 and ESRR induced regulator, muscle 1 Neighboring gene hes family bHLH transcription factor 4 Neighboring gene tyrosine-protein phosphatase non-receptor type 11-like Neighboring gene ring finger protein 223 Neighboring gene chromosome 16 C1orf159 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables laminin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled acetylcholine receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in receptor clustering IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
agrin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Strigops habroptila Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bStrHab1.2.pri

Genomic

  1. NC_044292.2 Reference bStrHab1.2.pri

    Range
    5336104..5445747
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030507766.1 → XP_030363626.1  agrin isoform X2

    UniProtKB/TrEMBL
    A0A672UUY1
    Conserved Domains (8) summary
    smart00280
    Location:496 → 541
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1149 → 1273
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1842 → 1872
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:1396 → 1546
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:1355 → 1383
    EGF; EGF-like domain
    pfam00054
    Location:1688 → 1819
    Laminin_G_1; Laminin G domain
    pfam00053
    Location:798 → 849
    Laminin_EGF; Laminin EGF domain
    pfam03146
    Location:30 → 145
    NtA; Agrin NtA domain

  2. XM_030507769.1 → XP_030363629.1  agrin isoform X5

    UniProtKB/TrEMBL
    A0A672UUY1
    Conserved Domains (8) summary
    smart00280
    Location:489 → 534
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1142 → 1266
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1835 → 1865
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:1389 → 1539
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:1348 → 1376
    EGF; EGF-like domain
    pfam00054
    Location:1681 → 1812
    Laminin_G_1; Laminin G domain
    pfam00053
    Location:791 → 842
    Laminin_EGF; Laminin EGF domain
    pfam03146
    Location:30 → 145
    NtA; Agrin NtA domain

  3. XM_030507765.1 → XP_030363625.1  agrin isoform X1

    UniProtKB/TrEMBL
    A0A672UUX5
    Conserved Domains (8) summary
    smart00280
    Location:496 → 541
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1149 → 1273
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1846 → 1876
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:1396 → 1546
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:1355 → 1383
    EGF; EGF-like domain
    pfam00054
    Location:1688 → 1823
    Laminin_G_1; Laminin G domain
    pfam00053
    Location:798 → 849
    Laminin_EGF; Laminin EGF domain
    pfam03146
    Location:30 → 145
    NtA; Agrin NtA domain

  4. XM_030507767.1 → XP_030363627.1  agrin isoform X3

    UniProtKB/TrEMBL
    A0A672UUX5
    Conserved Domains (8) summary
    smart00280
    Location:489 → 534
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1142 → 1266
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1839 → 1869
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:1389 → 1539
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:1348 → 1376
    EGF; EGF-like domain
    pfam00054
    Location:1681 → 1816
    Laminin_G_1; Laminin G domain
    pfam00053
    Location:791 → 842
    Laminin_EGF; Laminin EGF domain
    pfam03146
    Location:30 → 145
    NtA; Agrin NtA domain

  5. XM_030507768.1 → XP_030363628.1  agrin isoform X4

    UniProtKB/TrEMBL
    A0A672UUX5
    Conserved Domains (7) summary
    smart00280
    Location:392 → 437
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1045 → 1169
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1742 → 1772
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:1292 → 1442
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:1251 → 1279
    EGF; EGF-like domain
    pfam00054
    Location:1584 → 1719
    Laminin_G_1; Laminin G domain
    pfam00053
    Location:694 → 745
    Laminin_EGF; Laminin EGF domain
Nucleotide Protein
Heading Accession and Version

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