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INPP5B inositol polyphosphate-5-phosphatase B [ Strigops habroptila (Kakapo) ]

Gene ID: 115616155, updated on 3-Aug-2024

Summary

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Gene symbol
INPP5B
Gene description
inositol polyphosphate-5-phosphatase B
Gene type
protein coding
RefSeq status
MODEL
Organism
Strigops habroptila
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Psittaciformes; Psittacidae; Strigops
Orthologs
human mouse all
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Genomic context

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See INPP5B in Genome Data Viewer
Location:
chromosome: 12
Exon count:
24
Annotation release Status Assembly Chr Location
101 current bStrHab1.2.pri (GCF_004027225.2) 12 NC_044288.2 (5120492..5138553)
100 previous assembly bStrHab1_v1.p (GCF_004027225.1) 13 NC_044289.1 (5120492..5138553)

Chromosome 12 - NC_044288.2Genomic Context describing neighboring genes Neighboring gene four and a half LIM domains 3 Neighboring gene splicing factor 3a subunit 3 Neighboring gene metal regulatory transcription factor 1 Neighboring gene uncharacterized LOC116915281

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol-1,4,5-trisphosphate 5-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
type II inositol 1,4,5-trisphosphate 5-phosphatase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Strigops habroptila Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bStrHab1.2.pri

Genomic

  1. NC_044288.2 Reference bStrHab1.2.pri

    Range
    5120492..5138553
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030505069.1 → XP_030360929.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X3

    Conserved Domains (3) summary
    cd09093
    Location:213 → 506
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    pfam16776
    Location:1 → 123
    INPP5B_PH; Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain
    cl02570
    Location:640 → 688
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  2. XM_030505066.1 → XP_030360926.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1

    UniProtKB/TrEMBL
    A0A672UX70
    Conserved Domains (3) summary
    cd09093
    Location:213 → 506
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:640 → 857
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
    pfam16776
    Location:1 → 123
    INPP5B_PH; Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain

  3. XM_030505070.1 → XP_030360930.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X4

    Conserved Domains (3) summary
    cd09093
    Location:159 → 452
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:586 → 803
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
    cl17171
    Location:1 → 69
    PH-like; Pleckstrin homology-like domain

  4. XM_030505068.1 → XP_030360928.1  type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X2

    Conserved Domains (2) summary
    cd09093
    Location:97 → 390
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:524 → 741
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...

RNA

  1. XR_003994219.1 RNA Sequence

  2. XR_003994220.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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