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PLCB4 phospholipase C beta 4 [ Strigops habroptila (Kakapo) ]

Gene ID: 115609999, updated on 3-Aug-2024

Summary

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Gene symbol
PLCB4
Gene description
phospholipase C beta 4
Gene type
protein coding
RefSeq status
MODEL
Organism
Strigops habroptila
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Psittaciformes; Psittacidae; Strigops
Orthologs
human mouse all
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Genomic context

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See PLCB4 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
42
Annotation release Status Assembly Chr Location
101 current bStrHab1.2.pri (GCF_004027225.2) 6 NC_044282.2 (70367251..70564455, complement)
100 previous assembly bStrHab1_v1.p (GCF_004027225.1) 6 NC_044282.1 (70337014..70534006, complement)

Chromosome 6 - NC_044282.2Genomic Context describing neighboring genes Neighboring gene estradiol 17-beta-dehydrogenase 2-like Neighboring gene p21 (RAC1) activated kinase 5 Neighboring gene lysosomal associated membrane protein family member 5 Neighboring gene phospholipase C beta 1 Neighboring gene thioredoxin related transmembrane protein 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Strigops habroptila Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bStrHab1.2.pri

Genomic

  1. NC_044282.2 Reference bStrHab1.2.pri

    Range
    70367251..70564455 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030490897.2 → XP_030346757.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X4

    UniProtKB/TrEMBL
    A0A672UU60
    Conserved Domains (6) summary
    cd00275
    Location:702 → 818
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 668
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam15921
    Location:853 → 1169
    CCDC158; Coiled-coil domain-containing protein 158
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:914 → 955
    DUF1154; Protein of unknown function (DUF1154)

  2. XM_030490895.2 → XP_030346755.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X2

    UniProtKB/TrEMBL
    A0A672UU43
    Conserved Domains (6) summary
    cd00275
    Location:702 → 818
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 668
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam15921
    Location:853 → 1154
    CCDC158; Coiled-coil domain-containing protein 158
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:914 → 955
    DUF1154; Protein of unknown function (DUF1154)

  3. XM_030490896.2 → XP_030346756.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X3

    UniProtKB/TrEMBL
    A0A672UU60
    Conserved Domains (6) summary
    cd00275
    Location:714 → 830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam15921
    Location:865 → 1181
    CCDC158; Coiled-coil domain-containing protein 158
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:926 → 967
    DUF1154; Protein of unknown function (DUF1154)

  4. XM_030490891.2 → XP_030346751.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    UniProtKB/TrEMBL
    A0A672USP4
    Conserved Domains (6) summary
    cd00275
    Location:714 → 830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam15921
    Location:865 → 1166
    CCDC158; Coiled-coil domain-containing protein 158
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:926 → 967
    DUF1154; Protein of unknown function (DUF1154)

  5. XM_030490892.1 → XP_030346752.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    UniProtKB/TrEMBL
    A0A672USP4
    Conserved Domains (6) summary
    cd00275
    Location:714 → 830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam15921
    Location:865 → 1166
    CCDC158; Coiled-coil domain-containing protein 158
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:926 → 967
    DUF1154; Protein of unknown function (DUF1154)

  6. XM_030490893.1 → XP_030346753.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    UniProtKB/TrEMBL
    A0A672USP4
    Conserved Domains (6) summary
    cd00275
    Location:714 → 830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam15921
    Location:865 → 1166
    CCDC158; Coiled-coil domain-containing protein 158
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:926 → 967
    DUF1154; Protein of unknown function (DUF1154)

  7. XM_030490894.1 → XP_030346754.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    UniProtKB/TrEMBL
    A0A672USP4
    Conserved Domains (6) summary
    cd00275
    Location:714 → 830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam15921
    Location:865 → 1166
    CCDC158; Coiled-coil domain-containing protein 158
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:926 → 967
    DUF1154; Protein of unknown function (DUF1154)
Nucleotide Protein
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