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ALOX5 arachidonate 5-lipoxygenase [ Strigops habroptila (Kakapo) ]

Gene ID: 115608655, updated on 17-Mar-2024

Summary

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Gene symbol
ALOX5
Gene description
arachidonate 5-lipoxygenase
Gene type
protein coding
RefSeq status
MODEL
Organism
Strigops habroptila
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Strigops
Orthologs
human mouse all
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Genomic context

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See ALOX5 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
26
Annotation release Status Assembly Chr Location
101 current bStrHab1.2.pri (GCF_004027225.2) 5 NC_044281.2 (62094215..62142858, complement)
100 previous assembly bStrHab1_v1.p (GCF_004027225.1) 5 NC_044281.1 (62000778..62049421, complement)

Chromosome 5 - NC_044281.2Genomic Context describing neighboring genes Neighboring gene cytochrome P450 2H1-like Neighboring gene cytochrome P450 2H1-like Neighboring gene cytochrome P450 2H1-like Neighboring gene membrane associated ring-CH-type finger 8 Neighboring gene tolloid-like protein 2 Neighboring gene zona pellucida sperm-binding protein 4-like Neighboring gene cytochrome P450 2H2-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 5-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in xenobiotic metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nuclear envelope IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arachidonate 5-lipoxygenase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Strigops habroptila Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bStrHab1.2.pri

Genomic

  1. NC_044281.2 Reference bStrHab1.2.pri

    Range
    62094215..62142858 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030487813.1 → XP_030343673.1  arachidonate 5-lipoxygenase isoform X1

    Conserved Domains (3) summary
    cd01753
    Location:2 → 115
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00067
    Location:647 → 1104
    p450; Cytochrome P450
    pfam00305
    Location:227 → 579
    Lipoxygenase

  2. XM_030487815.1 → XP_030343675.1  arachidonate 5-lipoxygenase isoform X3

    Conserved Domains (2) summary
    pfam00067
    Location:212 → 669
    p450; Cytochrome P450
    pfam00305
    Location:29 → 144
    Lipoxygenase

  3. XM_030487818.1 → XP_030343678.1  arachidonate 5-lipoxygenase isoform X5

    UniProtKB/TrEMBL
    A0A672TMI1
    Conserved Domains (1) summary
    pfam00067
    Location:76 → 533
    p450; Cytochrome P450

  4. XM_030487817.1 → XP_030343677.1  arachidonate 5-lipoxygenase isoform X4

    UniProtKB/TrEMBL
    A0A672TMI1
    Conserved Domains (2) summary
    pfam00067
    Location:119 → 576
    p450; Cytochrome P450
    pfam00305
    Location:4 → 51
    Lipoxygenase

  5. XM_030487816.1 → XP_030343676.1  arachidonate 5-lipoxygenase isoform X4

    UniProtKB/TrEMBL
    A0A672TMI1
    Conserved Domains (2) summary
    pfam00067
    Location:119 → 576
    p450; Cytochrome P450
    pfam00305
    Location:4 → 51
    Lipoxygenase

  6. XM_030487814.1 → XP_030343674.1  arachidonate 5-lipoxygenase isoform X2

    Conserved Domains (2) summary
    cd01753
    Location:2 → 115
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:227 → 665
    Lipoxygenase
Nucleotide Protein
Heading Accession and Version

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