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HSPG2 heparan sulfate proteoglycan 2 [ Taeniopygia guttata (zebra finch) ]

Gene ID: 115497983, updated on 13-Aug-2024

Summary

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Gene symbol
HSPG2
Gene description
heparan sulfate proteoglycan 2
See related
Ensembl:ENSTGUG00000025761 Ensembl:ENSTGUG00000027523
Gene type
protein coding
RefSeq status
MODEL
Organism
Taeniopygia guttata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Passeroidea; Estrildidae; Estrildinae; Taeniopygia
Orthologs
human mouse all
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Genomic context

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See HSPG2 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
94
Annotation release Status Assembly Chr Location
106 current bTaeGut1.4.pri (GCF_003957565.2) 21 NC_044233.2 (5199097..5241578)
105 previous assembly bTaeGut2.pat.W.v2 (GCF_008822105.2) 21 NC_045019.1 (5098205..5141533)

Chromosome 21 - NC_044233.2Genomic Context describing neighboring genes Neighboring gene transmembrane protein 269 Neighboring gene chymotrypsin like elastase 3B Neighboring gene ubiquitin specific peptidase 48 Neighboring gene RAP1 GTPase activating protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
basement membrane-specific heparan sulfate proteoglycan core protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Taeniopygia guttata Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bTaeGut1.4.pri Primary Assembly

Genomic

  1. NC_044233.2 Reference bTaeGut1.4.pri Primary Assembly

    Range
    5199097..5241578
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032752093.2 → XP_032607984.2  basement membrane-specific heparan sulfate proteoglycan core protein

    Conserved Domains (12) summary
    cd05743
    Location:448 → 525
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00180
    Location:1298 → 1345
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1015 → 1137
    LamB; Laminin B domain
    smart00409
    Location:2962 → 3044
    IG; Immunoglobulin
    smart00410
    Location:2000 → 2077
    IG_like; Immunoglobulin like
    cd00054
    Location:3678 → 3711
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1183 → 1232
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:4009 → 4165
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:352 → 386
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00096
    Location:2011 → 2015
    Ig; Ig strand B [structural motif]
    cl02507
    Location:112 → 225
    SEA; SEA domain
    cl02548
    Location:1414 → 1517
    Laminin_B; Laminin B (Domain IV)
Nucleotide Protein
Heading Accession and Version

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