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PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [ Microcaecilia unicolor ]

Gene ID: 115479068, updated on 17-Mar-2024

Summary

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Gene symbol
PIK3CG
Gene description
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcaecilia unicolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Gymnophiona; Siphonopidae; Microcaecilia
Orthologs
human mouse all
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Genomic context

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See PIK3CG in Genome Data Viewer
Location:
chromosome: 10
Exon count:
14
Annotation release Status Assembly Chr Location
100 current aMicUni1.1 (GCF_901765095.1) 10 NC_044040.1 (35926800..35984204)

Chromosome 10 - NC_044040.1Genomic Context describing neighboring genes Neighboring gene nicotinamide phosphoribosyltransferase Neighboring gene coiled-coil domain containing 71 like Neighboring gene protein kinase cAMP-dependent type II regulatory subunit beta Neighboring gene HMG-box transcription factor 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_044040.1 Chromosome 10 Reference aMicUni1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multi-tissue transcriptomes of caecilian amphibians highlight incomplete knowledge of vertebrate gene families. Torres-Sánchez M, et al. DNA Res, 2019 Feb 1. PMID 30351380, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class IA IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class IB IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcaecilia unicolor Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference aMicUni1.1 Primary Assembly

Genomic

  1. NC_044040.1 Reference aMicUni1.1 Primary Assembly

    Range
    35926800..35984204
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030216796.1 → XP_030072656.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

    UniProtKB/TrEMBL
    A0A6P7ZAD5
    Conserved Domains (4) summary
    cd08399
    Location:350 → 530
    C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:552 → 728
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd00894
    Location:732 → 1098
    PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma
    cl02484
    Location:203 → 312
    PI3K_rbd; PI3-kinase family, ras-binding domain

  2. XM_030216797.1 → XP_030072657.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

    UniProtKB/TrEMBL
    A0A6P7ZAD5
    Conserved Domains (4) summary
    cd08399
    Location:350 → 530
    C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:552 → 728
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd00894
    Location:732 → 1098
    PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma
    cl02484
    Location:203 → 312
    PI3K_rbd; PI3-kinase family, ras-binding domain

  3. XM_030216798.1 → XP_030072658.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

    UniProtKB/TrEMBL
    A0A6P7ZAD5
    Conserved Domains (4) summary
    cd08399
    Location:350 → 530
    C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:552 → 728
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd00894
    Location:732 → 1098
    PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma
    cl02484
    Location:203 → 312
    PI3K_rbd; PI3-kinase family, ras-binding domain

  4. XM_030216799.1 → XP_030072659.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

    UniProtKB/TrEMBL
    A0A6P7ZAD5
    Conserved Domains (4) summary
    cd08399
    Location:350 → 530
    C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:552 → 728
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd00894
    Location:732 → 1098
    PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma
    cl02484
    Location:203 → 312
    PI3K_rbd; PI3-kinase family, ras-binding domain
Nucleotide Protein
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