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MASP1 MBL associated serine protease 1 [ Microcaecilia unicolor ]

Gene ID: 115478624, updated on 17-Mar-2024

Summary

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Gene symbol
MASP1
Gene description
MBL associated serine protease 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcaecilia unicolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Gymnophiona; Siphonopidae; Microcaecilia
Orthologs
human mouse all
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Genomic context

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See MASP1 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
18
Annotation release Status Assembly Chr Location
100 current aMicUni1.1 (GCF_901765095.1) 10 NC_044040.1 (214963939..215082699)

Chromosome 10 - NC_044040.1Genomic Context describing neighboring genes Neighboring gene BCL6 transcription repressor Neighboring gene somatostatin Neighboring gene receptor-transporting protein 3-like Neighboring gene uncharacterized LOC115479224

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_044040.1 Chromosome 10 Reference aMicUni1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multi-tissue transcriptomes of caecilian amphibians highlight incomplete knowledge of vertebrate gene families. Torres-Sánchez M, et al. DNA Res, 2019 Feb 1. PMID 30351380, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in zymogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in blood microparticle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mannan-binding lectin serine protease 1
Names
mannan binding lectin serine peptidase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcaecilia unicolor Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference aMicUni1.1 Primary Assembly

Genomic

  1. NC_044040.1 Reference aMicUni1.1 Primary Assembly

    Range
    214963939..215082699
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030216107.1 → XP_030071967.1  mannan-binding lectin serine protease 1 isoform X1

    UniProtKB/TrEMBL
    A0A6P7YXW1
    Conserved Domains (6) summary
    PHA02639
    Location:304 → 438
    PHA02639; EEV host range protein; Provisional
    smart00020
    Location:447 → 710
    Tryp_SPc; Trypsin-like serine protease
    smart00042
    Location:28 → 133
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    pfam00084
    Location:299 → 360
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:183 → 292
    CUB; CUB domain
    pfam14670
    Location:151 → 179
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  2. XM_030216110.1 → XP_030071970.1  mannan-binding lectin serine protease 1 isoform X4

    UniProtKB/TrEMBL
    A0A6P7Z968
    Conserved Domains (4) summary
    smart00042
    Location:28 → 133
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    pfam00084
    Location:299 → 360
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:183 → 292
    CUB; CUB domain
    pfam14670
    Location:151 → 179
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  3. XM_030216109.1 → XP_030071969.1  mannan-binding lectin serine protease 1 isoform X3

    UniProtKB/TrEMBL
    A0A6P7Z8E5
    Conserved Domains (6) summary
    PHA02639
    Location:304 → 430
    PHA02639; EEV host range protein; Provisional
    smart00042
    Location:28 → 133
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    cd00190
    Location:447 → 635
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:299 → 360
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:183 → 292
    CUB; CUB domain
    pfam14670
    Location:151 → 179
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  4. XM_030216108.1 → XP_030071968.1  mannan-binding lectin serine protease 1 isoform X2

    UniProtKB/TrEMBL
    A0A6P7Z3K9
    Conserved Domains (6) summary
    PHA02639
    Location:304 → 430
    PHA02639; EEV host range protein; Provisional
    smart00042
    Location:28 → 133
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    cd00190
    Location:447 → 691
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:299 → 360
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:183 → 292
    CUB; CUB domain
    pfam14670
    Location:151 → 179
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
Heading Accession and Version

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