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SHMT1 serine hydroxymethyltransferase 1 [ Microcaecilia unicolor ]

Gene ID: 115476745, updated on 17-Mar-2024

Summary

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Gene symbol
SHMT1
Gene description
serine hydroxymethyltransferase 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcaecilia unicolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Gymnophiona; Siphonopidae; Microcaecilia
Orthologs
human mouse all
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Genomic context

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See SHMT1 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
16
Annotation release Status Assembly Chr Location
100 current aMicUni1.1 (GCF_901765095.1) 8 NC_044038.1 (7945283..7989864)

Chromosome 8 - NC_044038.1Genomic Context describing neighboring genes Neighboring gene GRB2 related adaptor protein Neighboring gene solute carrier family 5 member 10 Neighboring gene family with sequence similarity 83 member G Neighboring gene phosphoribosyl pyrophosphate synthetase associated protein 2 Neighboring gene uncharacterized LOC115475341 Neighboring gene SMCR8-C9orf72 complex subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_044038.1 Chromosome 8 Reference aMicUni1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multi-tissue transcriptomes of caecilian amphibians highlight incomplete knowledge of vertebrate gene families. Torres-Sánchez M, et al. DNA Res, 2019 Feb 1. PMID 30351380, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cobalt ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glycine hydroxymethyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mRNA 5'-UTR binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mRNA regulatory element binding translation repressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-serine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in folic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycine biosynthetic process from serine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein homotetramerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in purine nucleobase biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine hydroxymethyltransferase, cytosolic

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcaecilia unicolor Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference aMicUni1.1 Primary Assembly

Genomic

  1. NC_044038.1 Reference aMicUni1.1 Primary Assembly

    Range
    7945283..7989864
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030213314.1 → XP_030069174.1  serine hydroxymethyltransferase, cytosolic isoform X3

    UniProtKB/TrEMBL
    A0A6P7Z0A2
    Conserved Domains (1) summary
    PLN03226
    Location:29 → 484
    PLN03226; serine hydroxymethyltransferase; Provisional

  2. XM_030213312.1 → XP_030069172.1  serine hydroxymethyltransferase, cytosolic isoform X3

    UniProtKB/TrEMBL
    A0A6P7Z0A2
    Conserved Domains (1) summary
    PLN03226
    Location:29 → 484
    PLN03226; serine hydroxymethyltransferase; Provisional

  3. XM_030213310.1 → XP_030069170.1  serine hydroxymethyltransferase, cytosolic isoform X1

    UniProtKB/TrEMBL
    A0A6P7Z105
    Conserved Domains (1) summary
    PLN03226
    Location:57 → 512
    PLN03226; serine hydroxymethyltransferase; Provisional

  4. XM_030213313.1 → XP_030069173.1  serine hydroxymethyltransferase, cytosolic isoform X3

    UniProtKB/TrEMBL
    A0A6P7Z0A2
    Conserved Domains (1) summary
    PLN03226
    Location:29 → 484
    PLN03226; serine hydroxymethyltransferase; Provisional

  5. XM_030213311.1 → XP_030069171.1  serine hydroxymethyltransferase, cytosolic isoform X2

    UniProtKB/TrEMBL
    A0A6P7YXA6
    Conserved Domains (1) summary
    PLN03226
    Location:54 → 509
    PLN03226; serine hydroxymethyltransferase; Provisional
Nucleotide Protein
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