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ALKBH8 alkB homolog 8, tRNA methyltransferase [ Aquila chrysaetos chrysaetos ]

Gene ID: 115353413, updated on 3-Aug-2024

Summary

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Gene symbol
ALKBH8
Gene description
alkB homolog 8, tRNA methyltransferase
See related
Ensembl:ENSACCG00020007723
Gene type
protein coding
RefSeq status
MODEL
Organism
Aquila chrysaetos chrysaetos (sub-species: chrysaetos)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Accipitrimorphae; Accipitriformes; Accipitridae; Accipitrinae; Aquila
Orthologs
human mouse all
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Genomic context

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See ALKBH8 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
15
Annotation release Status Assembly Chr Location
101 current bAquChr1.4 (GCF_900496995.4) 19 NC_044022.1 (10550716..10610440)

Chromosome 19 - NC_044022.1Genomic Context describing neighboring genes Neighboring gene sarcolipin Neighboring gene ELMO domain containing 1 Neighboring gene uncharacterized LOC121232451 Neighboring gene CWF19 like cell cycle control factor 2 Neighboring gene vitelline membrane outer layer protein 1-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_044022.1 Chromosome 19 Reference bAquChr1.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables S-adenosylmethionine-dependent methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tRNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tRNA wobble uridine modification IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alkylated DNA repair protein alkB homolog 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Aquila chrysaetos chrysaetos Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bAquChr1.4

Genomic

  1. NC_044022.1 Reference bAquChr1.4

    Range
    10550716..10610440
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030042787.2 → XP_029898647.1  alkylated DNA repair protein alkB homolog 8 isoform X4

    UniProtKB/TrEMBL
    A0A663EFX8, A0A663EGQ1
    Related
    ENSACCP00020011267.1
    Conserved Domains (4) summary
    cd12431
    Location:52 → 133
    RRM_ALKBH8; RNA recognition motif in alkylated DNA repair protein alkB homolog 8 (ALKBH8) and similar proteins
    pfam08241
    Location:427 → 516
    Methyltransf_11; Methyltransferase domain
    cl17173
    Location:409 → 436
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    cl21496
    Location:147 → 309
    2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily

  2. XM_030042786.2 → XP_029898646.1  alkylated DNA repair protein alkB homolog 8 isoform X2

    UniProtKB/TrEMBL
    A0A663EGQ1
    Related
    ENSACCP00020011293.1
    Conserved Domains (4) summary
    cd12431
    Location:52 → 133
    RRM_ALKBH8; RNA recognition motif in alkylated DNA repair protein alkB homolog 8 (ALKBH8) and similar proteins
    pfam08241
    Location:383 → 472
    Methyltransf_11; Methyltransferase domain
    cl17173
    Location:365 → 392
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    cl21496
    Location:79 → 265
    2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily

  3. XM_041118504.1 → XP_040974438.1  alkylated DNA repair protein alkB homolog 8 isoform X1

    UniProtKB/TrEMBL
    A0A663EGQ1, A0A663EHC1
    Conserved Domains (3) summary
    PRK08317
    Location:412 → 507
    PRK08317; hypothetical protein; Provisional
    smart00360
    Location:52 → 106
    RRM; RNA recognition motif
    cl21496
    Location:135 → 300
    2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily

  4. XM_041118505.1 → XP_040974439.1  alkylated DNA repair protein alkB homolog 8 isoform X1

    UniProtKB/TrEMBL
    A0A663EGQ1, A0A663EHC1
    Conserved Domains (3) summary
    PRK08317
    Location:412 → 507
    PRK08317; hypothetical protein; Provisional
    smart00360
    Location:52 → 106
    RRM; RNA recognition motif
    cl21496
    Location:135 → 300
    2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily

  5. XM_041118506.1 → XP_040974440.1  alkylated DNA repair protein alkB homolog 8 isoform X3

    UniProtKB/TrEMBL
    A0A663EGQ1
    Conserved Domains (3) summary
    PRK08317
    Location:356 → 451
    PRK08317; hypothetical protein; Provisional
    cl17169
    Location:1 → 50
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl21496
    Location:79 → 244
    2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily
Nucleotide Protein
Heading Accession and Version

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