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PKM pyruvate kinase M1/2 [ Aquila chrysaetos chrysaetos ]

Gene ID: 115342324, updated on 3-Aug-2024

Summary

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Gene symbol
PKM
Gene description
pyruvate kinase M1/2
See related
Ensembl:ENSACCG00020002502
Gene type
protein coding
RefSeq status
MODEL
Organism
Aquila chrysaetos chrysaetos (sub-species: chrysaetos)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Accipitrimorphae; Accipitriformes; Accipitridae; Accipitrinae; Aquila
Orthologs
human mouse all
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Genomic context

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See PKM in Genome Data Viewer
Location:
chromosome: 5
Exon count:
13
Annotation release Status Assembly Chr Location
101 current bAquChr1.4 (GCF_900496995.4) 5 NC_044008.1 (38648131..38669355, complement)

Chromosome 5 - NC_044008.1Genomic Context describing neighboring genes Neighboring gene SUMO peptidase family member, NEDD8 specific Neighboring gene GRAM domain containing 2A Neighboring gene poly(ADP-ribose) polymerase family member 6 Neighboring gene CUGBP Elav-like family member 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_044008.1 Chromosome 5 Reference bAquChr1.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyruvate kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pyruvate kinase PKM

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Aquila chrysaetos chrysaetos Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bAquChr1.4

Genomic

  1. NC_044008.1 Reference bAquChr1.4

    Range
    38648131..38669355 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030016445.1 → XP_029872305.1  pyruvate kinase PKM isoform X3

    UniProtKB/TrEMBL
    A0A663DUU8
    Conserved Domains (1) summary
    cd00288
    Location:41 → 529
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  2. XM_030016444.2 → XP_029872304.1  pyruvate kinase PKM isoform X2

    UniProtKB/TrEMBL
    A0A663DUU8
    Related
    ENSACCP00020003672.1

  3. XM_030016443.1 → XP_029872303.1  pyruvate kinase PKM isoform X1

    UniProtKB/TrEMBL
    A0A663DUU8
    Related
    ENSACCP00020003697.1, ENSACCT00020003841.1
    Conserved Domains (1) summary
    cd00288
    Location:61 → 549
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...
Nucleotide Protein
Heading Accession and Version

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