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tjp2a tight junction protein 2a (zona occludens 2) [ Cottoperca gobio ]

Gene ID: 115016644, updated on 17-Mar-2024

Summary

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Gene symbol
tjp2a
Gene description
tight junction protein 2a (zona occludens 2)
See related
Ensembl:ENSCGOG00000006890
Gene type
protein coding
RefSeq status
MODEL
Organism
Cottoperca gobio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Notothenioidei; Bovichtidae; Cottoperca
Orthologs
zebrafish all
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Genomic context

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See tjp2a in Genome Data Viewer
Location:
chromosome: 12
Exon count:
26
Annotation release Status Assembly Chr Location
100 current fCotGob3.1 (GCF_900634415.1) 12 NC_041366.1 (4476796..4511038)

Chromosome 12 - NC_041366.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC115016868 Neighboring gene phosphatidylinositol-4-phosphate 5-kinase, type I, beta a Neighboring gene amyloid-beta A4 precursor protein-binding family A member 1-like Neighboring gene MAM domain-containing protein 2-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041366.1 Chromosome 12 Reference fCotGob3.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cottoperca gobio Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fCotGob3.1

Genomic

  1. NC_041366.1 Reference fCotGob3.1

    Range
    4476796..4511038
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029444562.1 → XP_029300422.1  tight junction protein ZO-2-like isoform X2

    UniProtKB/TrEMBL
    A0A6J2QT27
    Related
    ENSCGOP00000014057.1, ENSCGOT00000015192.1

  2. XM_029444564.1 → XP_029300424.1  tight junction protein ZO-2-like isoform X3

    UniProtKB/TrEMBL
    A0A6J2QR76
    Related
    ENSCGOP00000014241.1, ENSCGOT00000015380.1

  3. XM_029444561.1 → XP_029300421.1  tight junction protein ZO-2-like isoform X1

    UniProtKB/TrEMBL
    A0A6J2QRR0
    Related
    ENSCGOP00000014228.1, ENSCGOT00000015367.1
    Conserved Domains (5) summary
    smart00072
    Location:771 → 949
    GuKc; Guanylate kinase homologues
    smart00228
    Location:368 → 445
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:222 → 344
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    cl17036
    Location:671 → 736
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein
Heading Accession and Version

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