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Psg25 pregnancy-specific beta-1-glycoprotein 25 [ Mus musculus (house mouse) ]

Gene ID: 114868, updated on 2-Nov-2024

Summary

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Official Symbol
Psg25provided by MGI
Official Full Name
pregnancy-specific beta-1-glycoprotein 25provided by MGI
Primary source
MGI:MGI:1891357
See related
Ensembl:ENSMUSG00000070798 AllianceGenome:MGI:1891357
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
cea13
Summary
Predicted to be involved in T cell activation and immune response. Predicted to be located in apical plasma membrane and cytosol. Predicted to be active in external side of plasma membrane. Orthologous to human CEACAM7 (CEA cell adhesion molecule 7). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward placenta adult (RPKM 47.8) See more
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Genomic context

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See Psg25 in Genome Data Viewer
Location:
7 A3; 7 9.15 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (18253627..18266191, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (18519702..18532266, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene pregnancy-specific beta-1-glycoprotein 26 Neighboring gene STARR-seq mESC enhancer starr_18169 Neighboring gene myotubularin related protein 2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_18170 Neighboring gene predicted gene, 26062 Neighboring gene pregnancy-specific beta-1-glycoprotein 27

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Clone Names

  • MGC117718

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in T cell activation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
  
is_active_in cellular_component ND
No biological Data available
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
pregnancy-specific beta-1-glycoprotein 25
Names
pregnancy-specific glycoprotein 25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_054060.1 → NP_473401.1  pregnancy-specific beta-1-glycoprotein 25

    See identical proteins and their annotated locations for NP_473401.1

    Status: PROVISIONAL

    Source sequence(s)
    BC100352
    Consensus CDS
    CCDS20872.1
    UniProtKB/TrEMBL
    Q497W1
    Related
    ENSMUSP00000092389.4, ENSMUST00000094795.5
    Conserved Domains (3) summary
    cd05774
    Location:156 → 260
    Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
    smart00408
    Location:400 → 461
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:393 → 472
    IG_like; Immunoglobulin like

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    18253627..18266191 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_881643.3 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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