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tlr18 toll-like receptor 18 [ Betta splendens (Siamese fighting fish) ]

Gene ID: 114843048, updated on 22-May-2024

Summary

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Gene symbol
tlr18
Gene description
toll-like receptor 18
Gene type
protein coding
RefSeq status
MODEL
Organism
Betta splendens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Anabantaria; Anabantiformes; Anabantoidei; Osphronemidae; Betta
Orthologs
zebrafish all
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Genomic context

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See tlr18 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2023_04 current fBetSpl5.4 (GCF_900634795.4) 16 NC_040896.2 (6454409..6460954, complement)
101 previous assembly fBetSpl5.3 (GCF_900634795.3) 16 NC_040896.1 (6598922..6605467, complement)

Chromosome 16 - NC_040896.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC129603210 Neighboring gene S100 calcium binding protein A1 Neighboring gene uncharacterized LOC114842504 Neighboring gene leucine rich repeat and Ig domain containing 4b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of heart contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
toll-like receptor 18
Names
toll-like receptor 2 type-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_900634795.4-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fBetSpl5.4 Primary Assembly

Genomic

  1. NC_040896.2 Reference fBetSpl5.4 Primary Assembly

    Range
    6454409..6460954 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029129245.2 → XP_028985078.1  toll-like receptor 18

    UniProtKB/TrEMBL
    A0A6P7KR94
    Conserved Domains (7) summary
    smart00255
    Location:663 → 802
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:58 → 551
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    cd05025
    Location:919 → 1009
    S-100A1; S-100A1 domain found in proteins similar to S100A1. S100A1 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy, to which this ...
    sd00031
    Location:60 → 83
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:372 → 399
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:83 → 141
    LRR_8; Leucine rich repeat
    cl29113
    Location:58 → 176
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
Nucleotide Protein
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