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Rpl31 ribosomal protein L31 [ Mus musculus (house mouse) ]

Gene ID: 114641, updated on 2-Nov-2024

Summary

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Official Symbol
Rpl31provided by MGI
Official Full Name
ribosomal protein L31provided by MGI
Primary source
MGI:MGI:2149632
See related
Ensembl:ENSMUSG00000073702 AllianceGenome:MGI:2149632
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Dts
Summary
A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in early conceptus and embryo. Orthologous to human RPL31 (ribosomal protein L31). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in liver E14 (RPKM 213.5), bladder adult (RPKM 185.2) and 24 other tissues See more
Orthologs
human all
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Genomic context

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See Rpl31 in Genome Data Viewer
Location:
1 B; 1 18.3 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (39406987..39410992)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (39367851..39371911)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene neuronal PAS domain protein 2 Neighboring gene ribosomal protein L17 pseudogene Neighboring gene STARR-seq mESC enhancer starr_00710 Neighboring gene predicted gene, 53549 Neighboring gene TBC1 domain family, member 8 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:39535681-39535790 Neighboring gene STARR-seq mESC enhancer starr_00719 Neighboring gene STARR-seq mESC enhancer starr_00720 Neighboring gene STARR-seq mESC enhancer starr_00721 Neighboring gene STARR-positive B cell enhancer ABC_E7719 Neighboring gene STARR-positive B cell enhancer ABC_E3270 Neighboring gene predicted gene, 24826 Neighboring gene predicted gene, 53550 Neighboring gene CCR4-NOT transcription complex, subunit 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum. Cabibbo A, et al. J Biol Chem, 2000 Feb 18. PMID 10671517
  2. Identification of Viral and Host Proteins That Interact with Murine Gammaherpesvirus 68 Latency-Associated Nuclear Antigen during Lytic Replication: a Role for Hsc70 in Viral Replication. Salinas E, et al. J Virol, 2016 Feb 1. PMID 26581985, Free PMC Article
  3. Transcription profile during maternal to zygotic transition in the mouse embryo. Li XY, et al. Reprod Fertil Dev, 2006. PMID 16930510
  4. CHIP as a membrane-shuttling proteostasis sensor. Kopp Y, et al. Elife, 2017 Nov 1. PMID 29091030, Free PMC Article
  5. Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders. Fairfield H, et al. Genome Res, 2015 Jul. PMID 25917818, Free PMC Article

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Spontaneous (2) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC106651, MGC107628

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cytoplasmic translation ISO
Inferred from Sequence Orthology
more info
  
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in ribosome NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
 PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
large ribosomal subunit protein eL31
Names
60S ribosomal protein L31

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001252218.2 → NP_001239147.1  large ribosomal subunit protein eL31

    See identical proteins and their annotated locations for NP_001239147.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1-3 encode the same protein.
    Source sequence(s)
    AC132571
    Consensus CDS
    CCDS14904.1
    UniProtKB/Swiss-Prot
    P62900
    UniProtKB/TrEMBL
    Q5M9K9, Q9CY93
    Related
    ENSMUSP00000137631.2, ENSMUST00000179954.8
    Conserved Domains (1) summary
    pfam01198
    Location:19 → 100
    Ribosomal_L31e; Ribosomal protein L31e

  2. NM_001252219.2 → NP_001239148.1  large ribosomal subunit protein eL31

    See identical proteins and their annotated locations for NP_001239148.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-3 encode the same protein.
    Source sequence(s)
    AC132571
    Consensus CDS
    CCDS14904.1
    UniProtKB/Swiss-Prot
    P62900
    UniProtKB/TrEMBL
    Q5M9K9, Q9CY93
    Related
    ENSMUSP00000136354.2, ENSMUST00000178079.8
    Conserved Domains (1) summary
    pfam01198
    Location:19 → 100
    Ribosomal_L31e; Ribosomal protein L31e

  3. NM_053257.4 → NP_444487.1  large ribosomal subunit protein eL31

    See identical proteins and their annotated locations for NP_444487.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-3 encode the same protein.
    Source sequence(s)
    AC132571
    Consensus CDS
    CCDS14904.1
    UniProtKB/Swiss-Prot
    P62900
    UniProtKB/TrEMBL
    Q5M9K9, Q9CY93
    Related
    ENSMUSP00000083722.7, ENSMUST00000086535.12
    Conserved Domains (1) summary
    pfam01198
    Location:19 → 100
    Ribosomal_L31e; Ribosomal protein L31e

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    39406987..39410992
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P62900.1 GenPept UniProtKB/Swiss-Prot:P62900

Gene LinkOut

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