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TJP2 tight junction protein 2 [ Podarcis muralis (Common wall lizard) ]

Gene ID: 114606272, updated on 15-Mar-2024

Summary

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Gene symbol
TJP2
Gene description
tight junction protein 2
See related
Ensembl:ENSPMRG00000015441
Gene type
protein coding
RefSeq status
MODEL
Organism
Podarcis muralis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Laterata; Lacertibaenia; Lacertidae; Podarcis
Orthologs
human mouse all
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Genomic context

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See TJP2 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
22
Annotation release Status Assembly Chr Location
100 current PodMur_1.0 (GCF_004329235.1) 11 NC_041322.1 (64562274..64614431, complement)

Chromosome 11 - NC_041322.1Genomic Context describing neighboring genes Neighboring gene amyloid beta precursor protein binding family A member 1 Neighboring gene endosomal transmembrane epsin interactor 1 Neighboring gene frataxin Neighboring gene phosphatidylinositol-4-phosphate 5-kinase type 1 beta

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041322.1 Chromosome 11 Reference PodMur_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Podarcis muralis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PodMur_1.0 Primary Assembly

Genomic

  1. NC_041322.1 Reference PodMur_1.0 Primary Assembly

    Range
    64562274..64614431 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028748306.1 → XP_028604139.1  tight junction protein ZO-2

    UniProtKB/TrEMBL
    A0A670JK11
    Related
    ENSPMRP00000023869.1, ENSPMRT00000025329.1
    Conserved Domains (6) summary
    cd12027
    Location:591 → 653
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00228
    Location:258 → 344
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:3 → 81
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:150 → 244
    SF-CC1; splicing factor, CC1-like family
    pfam00595
    Location:499 → 576
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cl17190
    Location:687 → 852
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
Nucleotide Protein
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