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OCRL OCRL inositol polyphosphate-5-phosphatase [ Podarcis muralis (Common wall lizard) ]

Gene ID: 114588964, updated on 15-Mar-2024

Summary

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Gene symbol
OCRL
Gene description
OCRL inositol polyphosphate-5-phosphatase
See related
Ensembl:ENSPMRG00000020654
Gene type
protein coding
RefSeq status
MODEL
Organism
Podarcis muralis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Laterata; Lacertibaenia; Lacertidae; Podarcis
Orthologs
human mouse all
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Genomic context

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See OCRL in Genome Data Viewer
Location:
chromosome: Z
Exon count:
24
Annotation release Status Assembly Chr Location
100 current PodMur_1.0 (GCF_004329235.1) Z NC_041330.1 (31979665..32007234)

Chromosome Z - NC_041330.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114589380 Neighboring gene midline 2 Neighboring gene uncharacterized LOC114589343 Neighboring gene X-prolyl aminopeptidase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041330.1 Chromosome Z Reference PodMur_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol phosphate phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
inositol polyphosphate 5-phosphatase OCRL-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Podarcis muralis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PodMur_1.0 Primary Assembly

Genomic

  1. NC_041330.1 Reference PodMur_1.0 Primary Assembly

    Range
    31979665..32007234
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028714811.1 → XP_028570644.1  inositol polyphosphate 5-phosphatase OCRL-1 isoform X1

    UniProtKB/TrEMBL
    A0A670K324, A0A670K519
    Related
    ENSPMRP00000031928.1, ENSPMRT00000033860.1
    Conserved Domains (3) summary
    cd09093
    Location:246 → 539
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:674 → 903
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
    pfam16726
    Location:23 → 119
    OCRL_clath_bd; Inositol polyphosphate 5-phosphatase clathrin binding domain

  2. XM_028714813.1 → XP_028570646.1  inositol polyphosphate 5-phosphatase OCRL-1 isoform X3

    UniProtKB/TrEMBL
    A0A670K6P3
    Related
    ENSPMRP00000031945.1, ENSPMRT00000033877.1
    Conserved Domains (3) summary
    cd09093
    Location:215 → 508
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:643 → 872
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
    pfam16726
    Location:23 → 120
    OCRL_clath_bd; Inositol polyphosphate 5-phosphatase clathrin binding domain

  3. XM_028714812.1 → XP_028570645.1  inositol polyphosphate 5-phosphatase OCRL-1 isoform X2

    UniProtKB/TrEMBL
    A0A670KAU5
    Related
    ENSPMRP00000031907.1, ENSPMRT00000033837.1
    Conserved Domains (3) summary
    cd09093
    Location:246 → 539
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:674 → 895
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
    pfam16726
    Location:23 → 119
    OCRL_clath_bd; Inositol polyphosphate 5-phosphatase clathrin binding domain
Nucleotide Protein
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