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tle2b TLE family member 2, transcriptional corepressor b [ Perca flavescens (yellow perch) ]

Gene ID: 114562170, updated on 15-Mar-2024

Summary

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Gene symbol
tle2b
Gene description
TLE family member 2, transcriptional corepressor b
Locus tag
EPR50_G00098280
Gene type
protein coding
RefSeq status
MODEL
Organism
Perca flavescens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Percoidei; Percidae; Percinae; Perca
Orthologs
zebrafish all
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Genomic context

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See tle2b in Genome Data Viewer
Location:
chromosome: 9
Exon count:
24
Annotation release Status Assembly Chr Location
100 current PFLA_1.0 (GCF_004354835.1) 9 NC_041339.1 (16691835..16784563, complement)

Chromosome 9 - NC_041339.1Genomic Context describing neighboring genes Neighboring gene phospholipid phosphatase 2b Neighboring gene TLE family member 2, transcriptional corepressor a Neighboring gene TLE family member 5, transcriptional modulator Neighboring gene guanine nucleotide-binding protein G(q) subunit alpha-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041339.1 Chromosome 9 Reference PFLA_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transducin-like enhancer protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Perca flavescens Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PFLA_1.0 Primary Assembly

Genomic

  1. NC_041339.1 Reference PFLA_1.0 Primary Assembly

    Range
    16691835..16784563 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028588476.1 → XP_028444277.1  transducin-like enhancer protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A484CZP0
    Conserved Domains (4) summary
    PHA03307
    Location:145 → 336
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00200
    Location:477 → 766
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:486 → 525
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 128
    TLE_N; Groucho/TLE N-terminal Q-rich domain

  2. XM_028588475.1 → XP_028444276.1  transducin-like enhancer protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A484CZP0
    Conserved Domains (4) summary
    PHA03307
    Location:145 → 336
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00200
    Location:477 → 766
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:486 → 525
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 128
    TLE_N; Groucho/TLE N-terminal Q-rich domain

  3. XM_028588477.1 → XP_028444278.1  transducin-like enhancer protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A484CZP0
    Conserved Domains (4) summary
    PHA03307
    Location:144 → 335
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00200
    Location:476 → 765
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:485 → 524
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 132
    TLE_N; Groucho/TLE N-terminal Q-rich domain

  4. XM_028588478.1 → XP_028444279.1  transducin-like enhancer protein 4 isoform X3

    Conserved Domains (4) summary
    PHA03307
    Location:76 → 267
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00200
    Location:408 → 697
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:417 → 456
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:9 → 59
    TLE_N; Groucho/TLE N-terminal Q-rich domain
Nucleotide Protein
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