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tjp2 tight junction protein 2 [ Perca flavescens (yellow perch) ]

Gene ID: 114555715, updated on 21-Dec-2023

Summary

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Gene symbol
tjp2
Gene description
tight junction protein 2
Locus tag
EPR50_G00045690
Gene type
protein coding
RefSeq status
MODEL
Organism
Perca flavescens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Percoidei; Percidae; Percinae; Perca
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Genomic context

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See tjp2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
24
Annotation release Status Assembly Chr Location
100 current PFLA_1.0 (GCF_004354835.1) 5 NC_041335.1 (649502..735701)

Chromosome 5 - NC_041335.1Genomic Context describing neighboring genes Neighboring gene 3-hydroxy-3-methylglutaryl-CoA reductase Neighboring gene frataxin Neighboring gene family with sequence similarity 189 member A2 Neighboring gene amyloid beta (A4) precursor protein-binding, family A, member 1a

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041335.1 Chromosome 5 Reference PFLA_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Perca flavescens Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PFLA_1.0 Primary Assembly

Genomic

  1. NC_041335.1 Reference PFLA_1.0 Primary Assembly

    Range
    649502..735701
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028578317.1 → XP_028434118.1  tight junction protein ZO-2 isoform X1

    UniProtKB/TrEMBL
    A0A484DAN1
    Conserved Domains (3) summary
    smart00072
    Location:666 → 844
    GuKc; Guanylate kinase homologues
    cd00992
    Location:33 → 118
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17036
    Location:567 → 632
    SH3; Src Homology 3 domain superfamily

  2. XM_028578318.1 → XP_028434119.1  tight junction protein ZO-2 isoform X2

    Conserved Domains (3) summary
    smart00072
    Location:666 → 844
    GuKc; Guanylate kinase homologues
    cd00992
    Location:33 → 118
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17036
    Location:567 → 632
    SH3; Src Homology 3 domain superfamily

  3. XM_028578319.1 → XP_028434120.1  tight junction protein ZO-2 isoform X3

    Conserved Domains (3) summary
    smart00072
    Location:666 → 844
    GuKc; Guanylate kinase homologues
    cd00992
    Location:33 → 118
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17036
    Location:567 → 632
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein
Heading Accession and Version

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