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psen1 presenilin 1 [ Perca flavescens (yellow perch) ]

Gene ID: 114546819, updated on 15-Mar-2024

Summary

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Gene symbol
psen1
Gene description
presenilin 1
Locus tag
EPR50_G00208410
Gene type
protein coding
RefSeq status
MODEL
Organism
Perca flavescens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Percoidei; Percidae; Percinae; Perca
Orthologs
zebrafish all
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Genomic context

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See psen1 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
11
Annotation release Status Assembly Chr Location
100 current PFLA_1.0 (GCF_004354835.1) 20 NC_041350.1 (26008833..26027004, complement)

Chromosome 20 - NC_041350.1Genomic Context describing neighboring genes Neighboring gene immunoglobulin lambda-1 light chain-like Neighboring gene T cell receptor alpha variable 1-2-like Neighboring gene papilin, proteoglycan like sulfated glycoprotein Neighboring gene enhancer of rudimentary homolog Neighboring gene exonuclease 3'-5' domain containing 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041350.1 Chromosome 20 Reference PFLA_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic endopeptidase activity, intramembrane cleaving IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables beta-catenin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch receptor processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in amyloid precursor protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in amyloid-beta metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in calcium ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in smooth endoplasmic reticulum calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in ciliary rootlet IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic shaft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in growth cone IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuromuscular junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
presenilin-1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Perca flavescens Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PFLA_1.0 Primary Assembly

Genomic

  1. NC_041350.1 Reference PFLA_1.0 Primary Assembly

    Range
    26008833..26027004 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028565904.1 → XP_028421705.1  presenilin-1-like

    UniProtKB/TrEMBL
    A0A484C5C4
    Conserved Domains (1) summary
    pfam01080
    Location:89 → 473
    Presenilin
Nucleotide Protein
Heading Accession and Version

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