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CHD4 chromodomain helicase DNA binding protein 4 [ Phyllostomus discolor (pale spear-nosed bat) ]

Gene ID: 114512672, updated on 30-Mar-2024

Summary

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Gene symbol
CHD4
Gene description
chromodomain helicase DNA binding protein 4
See related
EnsemblRapid:ENSPDIG00005017392
Gene type
protein coding
RefSeq status
MODEL
Organism
Phyllostomus discolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Phyllostominae; Phyllostomus
Orthologs
human mouse all
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Genomic context

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See CHD4 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
39
Annotation release Status Assembly Chr Location
101 current mPhyDis1.pri.v3 (GCF_004126475.2) 2 NC_040904.2 (195369863..195398994)
100 previous assembly mPhyDis1_v1.p (GCF_004126475.1) 2 Unlocalized Scaffold NW_021126247.1 (50131070..50160330)

Chromosome 2 - NC_040904.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC118498677 Neighboring gene acrosin binding protein Neighboring gene lysophosphatidic acid receptor 5 Neighboring gene keratin, type I cytoskeletal 18-like Neighboring gene small Cajal body-specific RNA 11 Neighboring gene NOP2 nucleolar protein Neighboring gene intermediate filament family orphan 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP-dependent chromatin remodeler activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NuRD complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
chromodomain-helicase-DNA-binding protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Phyllostomus discolor Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mPhyDis1.pri.v3

Genomic

  1. NC_040904.2 Reference mPhyDis1.pri.v3

    Range
    195369863..195398994
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036017306.1 → XP_035873199.1  chromodomain-helicase-DNA-binding protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A7E6D4G4
    Conserved Domains (10) summary
    PLN03142
    Location:724 → 1281
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:372 → 414
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:451 → 493
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:619 → 673
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:498 → 576
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18056
    Location:726 → 957
    DEXHc_CHD4; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 4
    pfam06461
    Location:1413 → 1549
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1302 → 1345
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:164 → 217
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1754 → 1879
    CHDCT2; CHDCT2 (NUC038) domain

  2. XM_036017309.1 → XP_035873202.1  chromodomain-helicase-DNA-binding protein 4 isoform X5

    UniProtKB/TrEMBL
    A0A7E6D1U8
    Conserved Domains (10) summary
    PLN03142
    Location:724 → 1281
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:372 → 414
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:451 → 493
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:619 → 673
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:498 → 576
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18056
    Location:726 → 957
    DEXHc_CHD4; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 4
    pfam06461
    Location:1385 → 1521
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1302 → 1345
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:164 → 217
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1726 → 1851
    CHDCT2; CHDCT2 (NUC038) domain

  3. XM_036017310.1 → XP_035873203.1  chromodomain-helicase-DNA-binding protein 4 isoform X7

    UniProtKB/TrEMBL
    A0A7E6D1S0
    Conserved Domains (10) summary
    PLN03142
    Location:724 → 1281
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:372 → 414
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:451 → 493
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:619 → 673
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:498 → 576
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18056
    Location:726 → 957
    DEXHc_CHD4; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 4
    pfam06461
    Location:1384 → 1520
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1301 → 1344
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:164 → 217
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1725 → 1850
    CHDCT2; CHDCT2 (NUC038) domain

  4. XM_036017312.1 → XP_035873205.1  chromodomain-helicase-DNA-binding protein 4 isoform X10

    UniProtKB/TrEMBL
    A0A7E6D1Q8
    Conserved Domains (10) summary
    PLN03142
    Location:711 → 1268
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:359 → 401
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:438 → 480
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:606 → 660
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:485 → 563
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18056
    Location:713 → 944
    DEXHc_CHD4; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 4
    pfam06461
    Location:1372 → 1508
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1289 → 1332
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:164 → 217
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1713 → 1838
    CHDCT2; CHDCT2 (NUC038) domain

  5. XM_036017311.1 → XP_035873204.1  chromodomain-helicase-DNA-binding protein 4 isoform X8

    UniProtKB/TrEMBL
    A0A7E6D4G8
    Conserved Domains (10) summary
    PLN03142
    Location:717 → 1274
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:365 → 407
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:444 → 486
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:612 → 666
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:491 → 569
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18056
    Location:719 → 950
    DEXHc_CHD4; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 4
    pfam06461
    Location:1378 → 1514
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1295 → 1338
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:157 → 210
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1719 → 1844
    CHDCT2; CHDCT2 (NUC038) domain

  6. XM_036017315.1 → XP_035873208.1  chromodomain-helicase-DNA-binding protein 4 isoform X12

    UniProtKB/TrEMBL
    A0A7E6D1S8
    Conserved Domains (10) summary
    PLN03142
    Location:704 → 1261
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:352 → 394
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:431 → 473
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:599 → 653
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:478 → 556
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18056
    Location:706 → 937
    DEXHc_CHD4; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 4
    pfam06461
    Location:1365 → 1501
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1282 → 1325
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:157 → 210
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1706 → 1831
    CHDCT2; CHDCT2 (NUC038) domain

  7. XM_028531629.2 → XP_028387430.1  chromodomain-helicase-DNA-binding protein 4 isoform X6

    UniProtKB/TrEMBL
    A0A6J2NBU9
    Conserved Domains (10) summary
    PLN03142
    Location:724 → 1281
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:372 → 414
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:451 → 493
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    pfam06461
    Location:1385 → 1521
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam08074
    Location:1726 → 1896
    CHDCT2; CHDCT2 (NUC038) domain
    pfam06465
    Location:1302 → 1351
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:164 → 217
    CHDNT; CHDNT (NUC034) domain
    cd18662
    Location:619 → 673
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:498 → 576
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18056
    Location:726 → 957
    DEXHc_CHD4; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 4

  8. XM_028531631.2 → XP_028387432.1  chromodomain-helicase-DNA-binding protein 4 isoform X9

    UniProtKB/TrEMBL
    A0A6J2N4K8
    Related
    ENSPDIP00005024584.2, ENSPDIT00005028446.2
    Conserved Domains (10) summary
    PLN03142
    Location:717 → 1274
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:365 → 407
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:444 → 486
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    pfam06461
    Location:1378 → 1514
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam08074
    Location:1719 → 1889
    CHDCT2; CHDCT2 (NUC038) domain
    pfam06465
    Location:1295 → 1344
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:157 → 210
    CHDNT; CHDNT (NUC034) domain
    cd18662
    Location:612 → 666
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:491 → 569
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18056
    Location:719 → 950
    DEXHc_CHD4; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 4

  9. XM_028531632.2 → XP_028387433.1  chromodomain-helicase-DNA-binding protein 4 isoform X13

    UniProtKB/TrEMBL
    A0A6J2NB54
    Conserved Domains (10) summary
    PLN03142
    Location:704 → 1261
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:352 → 394
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:431 → 473
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    pfam06461
    Location:1365 → 1501
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam08074
    Location:1706 → 1876
    CHDCT2; CHDCT2 (NUC038) domain
    pfam06465
    Location:1282 → 1331
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:157 → 210
    CHDNT; CHDNT (NUC034) domain
    cd18662
    Location:599 → 653
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:478 → 556
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18056
    Location:706 → 937
    DEXHc_CHD4; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 4

  10. XM_036017313.1 → XP_035873206.1  chromodomain-helicase-DNA-binding protein 4 isoform X11

    UniProtKB/TrEMBL
    A0A7E6D2L4
    Conserved Domains (10) summary
    PLN03142
    Location:711 → 1268
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:359 → 401
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:438 → 480
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:606 → 660
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:485 → 563
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18056
    Location:713 → 944
    DEXHc_CHD4; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 4
    pfam06461
    Location:1372 → 1508
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1289 → 1332
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:164 → 217
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1713 → 1838
    CHDCT2; CHDCT2 (NUC038) domain

  11. XM_028531628.2 → XP_028387429.1  chromodomain-helicase-DNA-binding protein 4 isoform X4

    UniProtKB/TrEMBL
    A0A6J2N6I6
    Conserved Domains (10) summary
    PLN03142
    Location:717 → 1274
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:365 → 407
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:444 → 486
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    pfam06461
    Location:1406 → 1542
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam08074
    Location:1747 → 1917
    CHDCT2; CHDCT2 (NUC038) domain
    pfam06465
    Location:1295 → 1344
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:157 → 210
    CHDNT; CHDNT (NUC034) domain
    cd18662
    Location:612 → 666
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:491 → 569
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18056
    Location:719 → 950
    DEXHc_CHD4; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 4

  12. XM_036017307.1 → XP_035873200.1  chromodomain-helicase-DNA-binding protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A7E6D1Q4
    Conserved Domains (10) summary
    PLN03142
    Location:724 → 1281
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:372 → 414
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:451 → 493
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:619 → 673
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:498 → 576
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18056
    Location:726 → 957
    DEXHc_CHD4; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 4
    pfam06461
    Location:1413 → 1549
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1302 → 1345
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:164 → 217
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1754 → 1879
    CHDCT2; CHDCT2 (NUC038) domain

  13. XM_036017308.1 → XP_035873201.1  chromodomain-helicase-DNA-binding protein 4 isoform X3

    UniProtKB/TrEMBL
    A0A7E6D2K9
    Conserved Domains (10) summary
    PLN03142
    Location:717 → 1274
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:365 → 407
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:444 → 486
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:612 → 666
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:491 → 569
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18056
    Location:719 → 950
    DEXHc_CHD4; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 4
    pfam06461
    Location:1406 → 1542
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1295 → 1338
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:157 → 210
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1747 → 1872
    CHDCT2; CHDCT2 (NUC038) domain
Nucleotide Protein
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