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SFRP1 secreted frizzled related protein 1 [ Phyllostomus discolor (pale spear-nosed bat) ]

Gene ID: 114508892, updated on 30-Mar-2024

Summary

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Gene symbol
SFRP1
Gene description
secreted frizzled related protein 1
See related
EnsemblRapid:ENSPDIG00005006415
Gene type
protein coding
RefSeq status
MODEL
Organism
Phyllostomus discolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Phyllostominae; Phyllostomus
Orthologs
human mouse all
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Genomic context

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See SFRP1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
4
Annotation release Status Assembly Chr Location
101 current mPhyDis1.pri.v3 (GCF_004126475.2) 11 NC_040913.2 (70410366..70450625)
100 previous assembly mPhyDis1_v1.p (GCF_004126475.1) 12 NC_040914.1 (39780102..39816809, complement)

Chromosome 11 - NC_040913.2Genomic Context describing neighboring genes Neighboring gene GINS complex subunit 4 Neighboring gene golgin A7 Neighboring gene zinc finger matrin-type 4 Neighboring gene transcriptional and immune response regulator

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
secreted frizzled-related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Phyllostomus discolor Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mPhyDis1.pri.v3

Genomic

  1. NC_040913.2 Reference mPhyDis1.pri.v3

    Range
    70410366..70450625
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036011574.1 → XP_035867467.1  secreted frizzled-related protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A7E6CKQ2
    Conserved Domains (2) summary
    cd07443
    Location:52 → 175
    CRD_SFRP1; Cysteine-rich domain of the secreted frizzled-related protein 1 (SFRP1), a regulator of Wnt activity
    cl02512
    Location:183 → 207
    NTR_like; NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the ...

  2. XM_028526955.2 → XP_028382756.1  secreted frizzled-related protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A6J2MT86
    Related
    ENSPDIP00005009071.1, ENSPDIT00005010542.2
    Conserved Domains (2) summary
    cd07443
    Location:52 → 175
    CRD_SFRP1; Cysteine-rich domain of the secreted frizzled-related protein 1 (SFRP1), a regulator of Wnt activity
    cd03580
    Location:183 → 306
    NTR_Sfrp1_like; NTR domain, Secreted frizzled-related protein (Sfrp) 1-like subfamily; composed of proteins similar to human Sfrp1, Sfrp2 and Sfrp5. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse ...
Nucleotide Protein
Heading Accession and Version

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