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STAT3 signal transducer and activator of transcription 3 [ Phyllostomus discolor (pale spear-nosed bat) ]

Gene ID: 114502756, updated on 11-Apr-2024

Summary

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Gene symbol
STAT3
Gene description
signal transducer and activator of transcription 3
See related
EnsemblRapid:ENSPDIG00005009431
Gene type
protein coding
RefSeq status
MODEL
Organism
Phyllostomus discolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Phyllostominae; Phyllostomus
Orthologs
human mouse all
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Genomic context

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See STAT3 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
24
Annotation release Status Assembly Chr Location
101 current mPhyDis1.pri.v3 (GCF_004126475.2) 8 NC_040910.2 (106470615..106526620, complement)
100 previous assembly mPhyDis1_v1.p (GCF_004126475.1) 8 NC_040910.1 (88415840..88473123, complement)

Chromosome 8 - NC_040910.2Genomic Context describing neighboring genes Neighboring gene signal transducer and activator of transcription 5B Neighboring gene signal transducer and activator of transcription 5A Neighboring gene caveolae associated protein 1 Neighboring gene zinc finger protein 212-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in growth hormone receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in leptin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to peptide hormone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal transducer and activator of transcription 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Phyllostomus discolor Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mPhyDis1.pri.v3

Genomic

  1. NC_040910.2 Reference mPhyDis1.pri.v3

    Range
    106470615..106526620 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028519920.2 → XP_028375721.1  signal transducer and activator of transcription 3 isoform X2

    UniProtKB/TrEMBL
    A0A6J2M890, A0A833ZP77
    Related
    ENSPDIP00005013538.1, ENSPDIT00005015638.2
    Conserved Domains (4) summary
    cd10374
    Location:554 → 714
    SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
    smart00964
    Location:2 → 120
    STAT_int; STAT protein, protein interaction domain
    cd16853
    Location:139 → 318
    STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
    cd16847
    Location:321 → 484
    STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

  2. XM_028519921.2 → XP_028375722.1  signal transducer and activator of transcription 3 isoform X3

    UniProtKB/TrEMBL
    A0A6J2M6W9, A0A834DZ25
    Conserved Domains (4) summary
    cd10374
    Location:554 → 715
    SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
    smart00964
    Location:2 → 120
    STAT_int; STAT protein, protein interaction domain
    cd16853
    Location:139 → 318
    STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
    cd16847
    Location:321 → 484
    STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

  3. XM_028519919.2 → XP_028375720.1  signal transducer and activator of transcription 3 isoform X1

    UniProtKB/TrEMBL
    A0A6J2MBK4, A0A834DZ25
    Conserved Domains (4) summary
    cd10374
    Location:554 → 715
    SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
    smart00964
    Location:2 → 120
    STAT_int; STAT protein, protein interaction domain
    cd16853
    Location:139 → 318
    STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
    cd16847
    Location:321 → 484
    STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

  4. XM_028519922.2 → XP_028375723.1  signal transducer and activator of transcription 3 isoform X4

    UniProtKB/TrEMBL
    A0A6J2MC73, A0A833ZP77
    Conserved Domains (4) summary
    cd10374
    Location:554 → 714
    SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
    smart00964
    Location:2 → 120
    STAT_int; STAT protein, protein interaction domain
    cd16853
    Location:139 → 318
    STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
    cd16847
    Location:321 → 484
    STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)
Nucleotide Protein
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