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CISH cytokine inducible SH2 containing protein [ Phyllostomus discolor (pale spear-nosed bat) ]

Gene ID: 114501715, updated on 30-Mar-2024

Summary

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Gene symbol
CISH
Gene description
cytokine inducible SH2 containing protein
See related
EnsemblRapid:ENSPDIG00005013634
Gene type
protein coding
RefSeq status
MODEL
Organism
Phyllostomus discolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Phyllostominae; Phyllostomus
Orthologs
human mouse all
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Genomic context

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See CISH in Genome Data Viewer
Location:
chromosome: 7
Exon count:
3
Annotation release Status Assembly Chr Location
101 current mPhyDis1.pri.v3 (GCF_004126475.2) 7 NC_040909.2 (3901397..3906383)
100 previous assembly mPhyDis1_v1.p (GCF_004126475.1) 7 NC_040909.1 (4196879..4200710)

Chromosome 7 - NC_040909.2Genomic Context describing neighboring genes Neighboring gene dedicator of cytokinesis 3 Neighboring gene RWD domain-containing protein 1-like Neighboring gene MAPK activated protein kinase 3 Neighboring gene chromosome 7 C3orf18 homolog Neighboring gene HemK methyltransferase family member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cytokine-inducible SH2-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Phyllostomus discolor Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mPhyDis1.pri.v3

Genomic

  1. NC_040909.2 Reference mPhyDis1.pri.v3

    Range
    3901397..3906383
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028518441.2 → XP_028374242.1  cytokine-inducible SH2-containing protein

    UniProtKB/TrEMBL
    A0A6J2M2H3
    Related
    ENSPDIP00005019366.1, ENSPDIT00005022404.2
    Conserved Domains (2) summary
    cd10718
    Location:73 → 160
    SH2_CIS; Src homology 2 (SH2) domain found in cytokine-inducible SH2-containing protein (CIS)
    cd03734
    Location:213 → 253
    SOCS_CIS1; SOCS (suppressors of cytokine signaling) box of CIS (cytokine-inducible SH2 protein) 1-like proteins. Together with the SOCS proteins, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. ...
Nucleotide Protein
Heading Accession and Version

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