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RELA RELA proto-oncogene, NF-kB subunit [ Phyllostomus discolor (pale spear-nosed bat) ]

Gene ID: 114499888, updated on 30-Mar-2024

Summary

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Gene symbol
RELA
Gene description
RELA proto-oncogene, NF-kB subunit
See related
EnsemblRapid:ENSPDIG00005007057
Gene type
protein coding
RefSeq status
MODEL
Organism
Phyllostomus discolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Phyllostominae; Phyllostomus
Orthologs
human mouse all
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Genomic context

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See RELA in Genome Data Viewer
Location:
chromosome: 6
Exon count:
11
Annotation release Status Assembly Chr Location
101 current mPhyDis1.pri.v3 (GCF_004126475.2) 6 NC_040908.2 (165912608..165922427, complement)
100 previous assembly mPhyDis1_v1.p (GCF_004126475.1) 6 NC_040908.1 (165376999..165386085, complement)

Chromosome 6 - NC_040908.2Genomic Context describing neighboring genes Neighboring gene pecanex 3 Neighboring gene signal-induced proliferation-associated 1 Neighboring gene lysine acetyltransferase 5 Neighboring gene ribonuclease H2 subunit C Neighboring gene adaptor related protein complex 5 subunit beta 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to cytokine IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor p65

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Phyllostomus discolor Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mPhyDis1.pri.v3

Genomic

  1. NC_040908.2 Reference mPhyDis1.pri.v3

    Range
    165912608..165922427 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028516395.2 → XP_028372196.1  transcription factor p65

    UniProtKB/TrEMBL
    A0A6J2LXY6, A0A834A558
    Related
    ENSPDIP00005009978.1, ENSPDIT00005011574.2
    Conserved Domains (2) summary
    cd07885
    Location:19 → 187
    RHD-n_RelA; N-terminal sub-domain of the Rel homology domain (RHD) of RelA
    cd01177
    Location:194 → 290
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
Nucleotide Protein
Heading Accession and Version

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