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Cbl E3 ubiquitin-protein ligase CBL [ Diabrotica virgifera virgifera (western corn rootworm) ]

Gene ID: 114327939, updated on 23-May-2024

Summary

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Gene symbol
Cbl
Gene description
E3 ubiquitin-protein ligase CBL
See related
EnsemblRapid:LOC114327939
Gene type
protein coding
RefSeq status
MODEL
Organism
Diabrotica virgifera virgifera (sub-species: virgifera)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia; Chrysomeloidea; Chrysomelidae; Galerucinae; Diabroticina; Diabroticites; Diabrotica
Orthologs
fruit fly all
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Genomic context

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See Cbl in Genome Data Viewer
Location:
chromosome: 6
Exon count:
8
Annotation release Status Assembly Chr Location
101 current PGI_DIABVI_V3a (GCF_917563875.1) 6 NC_065448.1 (109643549..109971898, complement)
100 previous assembly Dvir_v2.0 (GCF_003013835.1) Unplaced Scaffold NW_021038815.1 (347039..665141)

Chromosome 6 - NC_065448.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 85 Neighboring gene uncharacterized LOC114327941 Neighboring gene transfer RNA proline (anticodon CGG) Neighboring gene luciferin 4-monooxygenase-like Neighboring gene proton-coupled amino acid transporter 1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of epidermal growth factor-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase CBL-B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Diabrotica virgifera virgifera Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PGI_DIABVI_V3a

Genomic

  1. NC_065448.1 Reference PGI_DIABVI_V3a

    Range
    109643549..109971898 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028276660.2 → XP_028132461.1  E3 ubiquitin-protein ligase CBL-B

    UniProtKB/TrEMBL
    A0A6P7FA84
    Related
    XP_028132461.1, XM_028276660.2
    Conserved Domains (5) summary
    cd09920
    Location:240 → 336
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    cd14318
    Location:684 → 723
    UBA_Cbl_like; UBA domain found in casitas B-lineage lymphoma (Cbl) proteins
    pfam02262
    Location:38 → 159
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    cd16709
    Location:347 → 415
    RING-HC_Cbl-b; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-b and similar proteins
    pfam02761
    Location:163 → 246
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain
Nucleotide Protein
Heading Accession and Version

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