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GRK5 G protein-coupled receptor kinase 5 [ Eumetopias jubatus (Steller sea lion) ]

Gene ID: 114223030, updated on 15-Mar-2024

Summary

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Gene symbol
GRK5
Gene description
G protein-coupled receptor kinase 5
See related
EnsemblRapid:ENSEJUG00000014182
Gene type
protein coding
RefSeq status
MODEL
Organism
Eumetopias jubatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Otariidae; Eumetopias
Orthologs
human mouse all
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Genomic context

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See GRK5 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
100 current ASM402803v1 (GCF_004028035.1) Unplaced Scaffold NW_020998711.1 (2611972..2818582, complement)

NW_020998711.1Genomic Context describing neighboring genes Neighboring gene glutaredoxin-related protein 5, mitochondrial pseudogene Neighboring gene regulator of G protein signaling 10 Neighboring gene peroxiredoxin 3 Neighboring gene sideroflexin 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020998711 Unplaced Scaffold Reference ASM402803v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables G protein-coupled receptor kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
G protein-coupled receptor kinase 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Eumetopias jubatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM402803v1 Primary Assembly

Genomic

  1. NW_020998711.1 Reference ASM402803v1 Primary Assembly

    Range
    2611972..2818582 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028121729.1 → XP_027977530.1  G protein-coupled receptor kinase 5 isoform X4

    Related
    ENSEJUP00000019299.1, ENSEJUT00000021598.1
    Conserved Domains (2) summary
    cd08752
    Location:53 → 175
    RGS_GRK5; Regulator of G protein signaling domain (RGS) found in G protein-coupled receptor kinase 5 (GRK5)
    cd05632
    Location:183 → 495
    STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5

  2. XM_028121726.1 → XP_027977527.1  G protein-coupled receptor kinase 5 isoform X1

    Related
    ENSEJUP00000019240.1, ENSEJUT00000021531.1
    Conserved Domains (2) summary
    cd08752
    Location:53 → 175
    RGS_GRK5; Regulator of G protein signaling domain (RGS) found in G protein-coupled receptor kinase 5 (GRK5)
    cl21453
    Location:183 → 540
    PKc_like; Protein Kinases, catalytic domain

  3. XM_028121728.1 → XP_027977529.1  G protein-coupled receptor kinase 5 isoform X3

    Related
    ENSEJUP00000019265.1, ENSEJUT00000021561.1
    Conserved Domains (2) summary
    cd08752
    Location:21 → 143
    RGS_GRK5; Regulator of G protein signaling domain (RGS) found in G protein-coupled receptor kinase 5 (GRK5)
    cl21453
    Location:151 → 508
    PKc_like; Protein Kinases, catalytic domain

  4. XM_028121727.1 → XP_027977528.1  G protein-coupled receptor kinase 5 isoform X2

    Conserved Domains (2) summary
    cd08752
    Location:50 → 172
    RGS_GRK5; Regulator of G protein signaling domain (RGS) found in G protein-coupled receptor kinase 5 (GRK5)
    cl21453
    Location:180 → 537
    PKc_like; Protein Kinases, catalytic domain

  5. XM_028121730.1 → XP_027977531.1  G protein-coupled receptor kinase 5 isoform X5

    Conserved Domains (2) summary
    cd05605
    Location:185 → 422
    STKc_GRK4_like; Catalytic domain of G protein-coupled Receptor Kinase 4-like Serine/Threonine Kinases
    cl02565
    Location:53 → 175
    RGS; Regulator of G protein signaling (RGS) domain superfamily
Nucleotide Protein
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