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HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 [ Zalophus californianus (California sea lion) ]

Gene ID: 113929065, updated on 15-Mar-2024

Summary

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Gene symbol
HMGCS1
Gene description
3-hydroxy-3-methylglutaryl-CoA synthase 1
See related
EnsemblRapid:ENSZCAG00025002357
Gene type
protein coding
RefSeq status
MODEL
Organism
Zalophus californianus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Otariidae; Zalophus
Orthologs
human mouse all
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Genomic context

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See HMGCS1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
12
Annotation release Status Assembly Chr Location
101 current mZalCal1.pri.v2 (GCF_009762305.2) 5 NC_045599.1 (120147196..120167197)
100 previous assembly zalCal2.2 (GCF_900631625.1) Unplaced Scaffold NW_020874474.1 (33939762..33959768, complement)

Chromosome 5 - NC_045599.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 267 Neighboring gene C-C motif chemokine ligand 28 Neighboring gene NIM1 serine/threonine protein kinase Neighboring gene zinc finger protein 131

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA synthase, cytoplasmic

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Zalophus californianus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mZalCal1.pri.v2 Primary Assembly

Genomic

  1. NC_045599.1 Reference mZalCal1.pri.v2 Primary Assembly

    Range
    120147196..120167197
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027605617.2 → XP_027461418.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    UniProtKB/TrEMBL
    A0A6J2E373
    Conserved Domains (1) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

  2. XM_027605616.2 → XP_027461417.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    UniProtKB/TrEMBL
    A0A6J2E373
    Related
    ENSZCAP00025003591.1, ENSZCAT00025004103.1
    Conserved Domains (1) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

  3. XM_027605615.2 → XP_027461416.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    UniProtKB/TrEMBL
    A0A6J2E373
    Conserved Domains (1) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
Nucleotide Protein
Heading Accession and Version

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