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PTEN phosphatase and tensin homolog [ Zalophus californianus (California sea lion) ]

Gene ID: 113918785, updated on 15-Mar-2024

Summary

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Gene symbol
PTEN
Gene description
phosphatase and tensin homolog
Gene type
protein coding
RefSeq status
MODEL
Organism
Zalophus californianus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Otariidae; Zalophus
Orthologs
human mouse all
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Genomic context

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See PTEN in Genome Data Viewer
Location:
chromosome: 15
Exon count:
6
Annotation release Status Assembly Chr Location
101 current mZalCal1.pri.v2 (GCF_009762305.2) 15 NC_045609.1 (7539946..7563247)
100 previous assembly zalCal2.2 (GCF_900631625.1) Unplaced Scaffold NW_020874462.1 (79677233..79700531, complement)

Chromosome 15 - NC_045609.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC113921789 Neighboring gene ATPase family AAA domain containing 1 Neighboring gene phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN-like Neighboring gene peroxisomal biogenesis factor 19-like Neighboring gene renalase, FAD dependent amine oxidase Neighboring gene 40S ribosomal protein S24-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell motility IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Zalophus californianus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mZalCal1.pri.v2 Primary Assembly

Genomic

  1. NC_045609.1 Reference mZalCal1.pri.v2 Primary Assembly

    Range
    7539946..7563247
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027587595.2 → XP_027443396.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

    UniProtKB/TrEMBL
    A0A6J2CJ83
    Conserved Domains (2) summary
    pfam10409
    Location:26 → 187
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl28904
    Location:3 → 19
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
Nucleotide Protein
Heading Accession and Version

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