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CISH cytokine inducible SH2 containing protein [ Zalophus californianus (California sea lion) ]

Gene ID: 113918702, updated on 15-Mar-2024

Summary

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Gene symbol
CISH
Gene description
cytokine inducible SH2 containing protein
See related
EnsemblRapid:ENSZCAG00025008053
Gene type
protein coding
RefSeq status
MODEL
Organism
Zalophus californianus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Otariidae; Zalophus
Orthologs
human mouse all
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Genomic context

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See CISH in Genome Data Viewer
Location:
chromosome: 1
Exon count:
4
Annotation release Status Assembly Chr Location
101 current mZalCal1.pri.v2 (GCF_009762305.2) 1 NC_045595.1 (19543491..19548835, complement)
100 previous assembly zalCal2.2 (GCF_900631625.1) Unplaced Scaffold NW_020884868.1 (193673142..193678489)

Chromosome 1 - NC_045595.1Genomic Context describing neighboring genes Neighboring gene chromosome 1 C3orf18 homolog Neighboring gene HemK methyltransferase family member 1 Neighboring gene uncharacterized LOC113918703 Neighboring gene MAPK activated protein kinase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cytokine-inducible SH2-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Zalophus californianus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mZalCal1.pri.v2 Primary Assembly

Genomic

  1. NC_045595.1 Reference mZalCal1.pri.v2 Primary Assembly

    Range
    19543491..19548835 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027587409.2 → XP_027443210.2  cytokine-inducible SH2-containing protein isoform X1

    UniProtKB/TrEMBL
    A0A6J2CG27
    Related
    ENSZCAP00025012338.1, ENSZCAT00025014082.1
    Conserved Domains (2) summary
    cd10718
    Location:77 → 164
    SH2_CIS; Src homology 2 (SH2) domain found in cytokine-inducible SH2-containing protein (CIS)
    cd03734
    Location:217 → 257
    SOCS_CIS1; SOCS (suppressors of cytokine signaling) box of CIS (cytokine-inducible SH2 protein) 1-like proteins. Together with the SOCS proteins, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. ...

  2. XM_027587410.2 → XP_027443211.2  cytokine-inducible SH2-containing protein isoform X2

    UniProtKB/TrEMBL
    A0A6J2CIN4
    Conserved Domains (2) summary
    cd10718
    Location:115 → 202
    SH2_CIS; Src homology 2 (SH2) domain found in cytokine-inducible SH2-containing protein (CIS)
    cd03734
    Location:255 → 295
    SOCS_CIS1; SOCS (suppressors of cytokine signaling) box of CIS (cytokine-inducible SH2 protein) 1-like proteins. Together with the SOCS proteins, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. ...
Nucleotide Protein
Heading Accession and Version

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