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GRK5 G protein-coupled receptor kinase 5 [ Zalophus californianus (California sea lion) ]

Gene ID: 113918530, updated on 15-Mar-2024

Summary

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Gene symbol
GRK5
Gene description
G protein-coupled receptor kinase 5
See related
EnsemblRapid:ENSZCAG00025022911
Gene type
protein coding
RefSeq status
MODEL
Organism
Zalophus californianus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Otariidae; Zalophus
Orthologs
human mouse all
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Genomic context

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See GRK5 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
17
Annotation release Status Assembly Chr Location
101 current mZalCal1.pri.v2 (GCF_009762305.2) 15 NC_045609.1 (76636372..76843870)
100 previous assembly zalCal2.2 (GCF_900631625.1) Unplaced Scaffold NW_020874462.1 (12014807..12221449, complement)

Chromosome 15 - NC_045609.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC113918560 Neighboring gene peroxiredoxin 3 Neighboring gene uncharacterized LOC113918563 Neighboring gene regulator of G protein signaling 10 Neighboring gene glutaredoxin-related protein 5, mitochondrial-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables G protein-coupled receptor kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
G protein-coupled receptor kinase 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Zalophus californianus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mZalCal1.pri.v2 Primary Assembly

Genomic

  1. NC_045609.1 Reference mZalCal1.pri.v2 Primary Assembly

    Range
    76636372..76843870
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027587046.1 → XP_027442847.1  G protein-coupled receptor kinase 5 isoform X1

    UniProtKB/TrEMBL
    A0A6J2CJJ4
    Related
    ENSZCAP00025036357.1, ENSZCAT00025041039.1
    Conserved Domains (2) summary
    cd08752
    Location:53 → 175
    RGS_GRK5; Regulator of G protein signaling domain (RGS) found in G protein-coupled receptor kinase 5 (GRK5)
    cl21453
    Location:183 → 540
    PKc_like; Protein Kinases, catalytic domain

  2. XM_027587060.1 → XP_027442861.1  G protein-coupled receptor kinase 5 isoform X3

    UniProtKB/TrEMBL
    A0A6J2CHK1
    Related
    ENSZCAP00025036444.1, ENSZCAT00025041146.1

  3. XM_027587077.1 → XP_027442878.1  G protein-coupled receptor kinase 5 isoform X5

    UniProtKB/TrEMBL
    A0A6J2CL98
    Related
    ENSZCAP00025036509.1, ENSZCAT00025041218.1
    Conserved Domains (2) summary
    cd08752
    Location:53 → 175
    RGS_GRK5; Regulator of G protein signaling domain (RGS) found in G protein-coupled receptor kinase 5 (GRK5)
    cd05632
    Location:183 → 495
    STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5

  4. XM_027587055.2 → XP_027442856.1  G protein-coupled receptor kinase 5 isoform X2

    UniProtKB/TrEMBL
    A0A6J2CHJ6
    Related
    ENSZCAP00025036399.1, ENSZCAT00025041090.1

  5. XM_027587086.2 → XP_027442887.1  G protein-coupled receptor kinase 5 isoform X6

    UniProtKB/TrEMBL
    A0A6J2CJN6

  6. XM_027587068.2 → XP_027442869.1  G protein-coupled receptor kinase 5 isoform X4

    UniProtKB/TrEMBL
    A0A6J2CG99
    Related
    ENSZCAP00025036483.1, ENSZCAT00025041190.1
    Conserved Domains (2) summary
    cd08752
    Location:21 → 143
    RGS_GRK5; Regulator of G protein signaling domain (RGS) found in G protein-coupled receptor kinase 5 (GRK5)
    cl21453
    Location:151 → 508
    PKc_like; Protein Kinases, catalytic domain

  7. XM_027587094.1 → XP_027442895.1  G protein-coupled receptor kinase 5 isoform X7

    UniProtKB/TrEMBL
    A0A6J2CF69

RNA

  1. XR_003518608.1 RNA Sequence

  2. XR_003518609.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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