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CAPN3 calpain 3 [ Zalophus californianus (California sea lion) ]

Gene ID: 113910306, updated on 15-Mar-2024

Summary

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Gene symbol
CAPN3
Gene description
calpain 3
See related
EnsemblRapid:ENSZCAG00025003528
Gene type
protein coding
RefSeq status
MODEL
Organism
Zalophus californianus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Otariidae; Zalophus
Orthologs
human mouse all
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Genomic context

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See CAPN3 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
26
Annotation release Status Assembly Chr Location
101 current mZalCal1.pri.v2 (GCF_009762305.2) 6 NC_045600.1 (84307122..84354112)
100 previous assembly zalCal2.2 (GCF_900631625.1) Unplaced Scaffold NW_020876041.1 (60303401..60350380, complement)

Chromosome 6 - NC_045600.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 87A Neighboring gene U6 spliceosomal RNA Neighboring gene glucosidase alpha, neutral C Neighboring gene zinc finger protein 106 Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene synaptosome associated protein 23

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Zalophus californianus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mZalCal1.pri.v2 Primary Assembly

Genomic

  1. NC_045600.1 Reference mZalCal1.pri.v2 Primary Assembly

    Range
    84307122..84354112
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027572315.2 → XP_027428116.1  calpain-3 isoform X1

    UniProtKB/TrEMBL
    A0A6J2BAU8
    Related
    ENSZCAP00025005939.1, ENSZCAT00025006761.1
    Conserved Domains (4) summary
    pfam16648
    Location:583 → 653
    Calpain_u2; Unstructured region on Calpain-3
    cd16190
    Location:653 → 821
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:75 → 415
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:436 → 579
    Calpain_III; Calpain large subunit, domain III

  2. XM_027572316.2 → XP_027428117.1  calpain-3 isoform X2

    UniProtKB/TrEMBL
    A0A6J2BCU9

  3. XM_027572318.2 → XP_027428119.1  calpain-3 isoform X4

    UniProtKB/TrEMBL
    A0A6J2B896
    Related
    ENSZCAP00025006029.1, ENSZCAT00025006870.1
    Conserved Domains (3) summary
    cd16190
    Location:561 → 729
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:75 → 367
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:388 → 531
    Calpain_III; Calpain large subunit, domain III

  4. XM_027572319.2 → XP_027428120.1  calpain-3 isoform X5

    UniProtKB/TrEMBL
    A0A6J2B866

  5. XM_027572317.2 → XP_027428118.1  calpain-3 isoform X3

    UniProtKB/TrEMBL
    A0A6J2BEB5

  6. XM_027572320.2 → XP_027428121.1  calpain-3 isoform X6

    UniProtKB/TrEMBL
    A0A6J2BAV6
Nucleotide Protein
Heading Accession and Version

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