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tjp2a tight junction protein 2a (zona occludens 2) [ Electrophorus electricus (electric eel) ]

Gene ID: 113575593, updated on 18-Jun-2024

Summary

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Gene symbol
tjp2a
Gene description
tight junction protein 2a (zona occludens 2)
See related
Ensembl:ENSEEEG00000011653
Gene type
protein coding
RefSeq status
MODEL
Organism
Electrophorus electricus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Gymnotiformes; Gymnotoidei; Gymnotidae; Electrophorus
Also known as
tjp2
Orthologs
zebrafish all
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Genomic context

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See tjp2a in Genome Data Viewer
Location:
chromosome: 17
Exon count:
25
Annotation release Status Assembly Chr Location
101 current fEleEle1.pri (GCF_013358815.1) 17 NC_049551.1 (11613428..11632076, complement)
100 previous assembly Ee_SOAP_WITH_SSPACE (GCF_003665695.1) Unplaced Scaffold NW_020825947.1 (1358418..1371027, complement)

Chromosome 17 - NC_049551.1Genomic Context describing neighboring genes Neighboring gene MAM domain containing 2b Neighboring gene amyloid beta (A4) precursor protein-binding, family A, member 1b Neighboring gene phosphatidylinositol-4-phosphate 5-kinase, type I, beta a Neighboring gene uncharacterized LOC113576458

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2a
Names
tight junction protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Electrophorus electricus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fEleEle1.pri

Genomic

  1. NC_049551.1 Reference fEleEle1.pri

    Range
    11613428..11632076 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035535252.1 → XP_035391145.1  tight junction protein ZO-2a isoform X2

    UniProtKB/TrEMBL
    A0A4W4FIL7
    Related
    ENSEEEP00000053429.1, ENSEEET00000060830.1
    Conserved Domains (6) summary
    TIGR00934
    Location:189 → 329
    2a38euk; potassium uptake protein, Trk family
    smart00072
    Location:749 → 927
    GuKc; Guanylate kinase homologues
    smart00228
    Location:556 → 638
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:11 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:154 → 238
    SF-CC1; splicing factor, CC1-like family
    cl17036
    Location:650 → 715
    SH3; Src Homology 3 domain superfamily

  2. XM_027007177.2 → XP_026862978.2  tight junction protein ZO-2a isoform X1

    UniProtKB/TrEMBL
    A0A4W4FIL7
    Conserved Domains (6) summary
    TIGR00934
    Location:212 → 352
    2a38euk; potassium uptake protein, Trk family
    smart00072
    Location:772 → 950
    GuKc; Guanylate kinase homologues
    smart00228
    Location:579 → 661
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:34 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:177 → 261
    SF-CC1; splicing factor, CC1-like family
    cl17036
    Location:673 → 738
    SH3; Src Homology 3 domain superfamily

  3. XM_035535251.1 → XP_035391144.1  tight junction protein ZO-2a isoform X2

    UniProtKB/TrEMBL
    A0A4W4FIL7
    Conserved Domains (6) summary
    TIGR00934
    Location:189 → 329
    2a38euk; potassium uptake protein, Trk family
    smart00072
    Location:749 → 927
    GuKc; Guanylate kinase homologues
    smart00228
    Location:556 → 638
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:11 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:154 → 238
    SF-CC1; splicing factor, CC1-like family
    cl17036
    Location:650 → 715
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein
Heading Accession and Version

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