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TOP3A DNA topoisomerase III alpha [ Pseudonaja textilis ]

Gene ID: 113438846, updated on 15-Mar-2024

Summary

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Gene symbol
TOP3A
Gene description
DNA topoisomerase III alpha
See related
Ensembl:ENSPTXG00000003051
Gene type
protein coding
RefSeq status
MODEL
Organism
Pseudonaja textilis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Elapidae; Acanthophiinae; Pseudonaja
Orthologs
human mouse all
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Genomic context

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See TOP3A in Genome Data Viewer
Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
100 current EBS10Xv2-PRI (GCF_900518735.1) Unplaced Scaffold NW_020769332.1 (14910282..14921877, complement)

NW_020769332.1Genomic Context describing neighboring genes Neighboring gene FLII actin remodeling protein Neighboring gene mitochondrial elongation factor 2 Neighboring gene SMCR8-C9orf72 complex subunit Neighboring gene serine hydroxymethyltransferase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020769332 Unplaced Scaffold Reference EBS10Xv2-PRI

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA topoisomerase type I (single strand cut, ATP-independent) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA topological change IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA topoisomerase 3-alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pseudonaja textilis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EBS10Xv2-PRI

Genomic

  1. NW_020769332.1 Reference EBS10Xv2-PRI

    Range
    14910282..14921877 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026704418.1 → XP_026560203.1  DNA topoisomerase 3-alpha

    UniProtKB/TrEMBL
    A0A670Y6B2
    Related
    ENSPTXP00000004120.1, ENSPTXT00000004240.1
    Conserved Domains (4) summary
    cd03362
    Location:37 → 195
    TOPRIM_TopoIA_TopoIII; The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving one strand of the DNA ...
    cd00186
    Location:204 → 619
    TOP1Ac; DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA ...
    pfam06839
    Location:901 → 945
    zf-GRF; GRF zinc finger
    pfam01396
    Location:657 → 696
    zf-C4_Topoisom; Topoisomerase DNA binding C4 zinc finger
Nucleotide Protein
Heading Accession and Version

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