SHMT1 serine hydroxymethyltransferase 1 [Ursus arctos (brown bear)] - Gene

Summary

Gene symbol: SHMT1
Gene description: serine hydroxymethyltransferase 1
See related: EnsemblRapid:ENSUARG00005006479
Gene type: protein coding
RefSeq status: MODEL
Organism: Ursus arctos
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2023_06	current	UrsArc2.0 (GCF_023065955.2)	Unplaced Scaffold	NW_026622808.1 (1586658..1611006, complement)
102	previous assembly	UrsArc1.0 (GCF_023065955.1)	Unplaced Scaffold	NW_025929761.1 (70050842..70075191)

NW_026622808.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables cobalt ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables glycine hydroxymethyltransferase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables mRNA 5'-UTR binding	IEA Inferred from Electronic Annotation more info	PubMed
enables mRNA regulatory element binding translation repressor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein homodimerization activity	IEA Inferred from Electronic Annotation more info	PubMed
enables pyridoxal phosphate binding	IEA Inferred from Electronic Annotation more info	PubMed
enables serine binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in L-serine catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to leukemia inhibitory factor	IEA Inferred from Electronic Annotation more info	PubMed
involved_in folic acid metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in glycine biosynthetic process from serine	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein homotetramerization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in purine nucleobase biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in tetrahydrofolate interconversion	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed