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ACACA acetyl-CoA carboxylase alpha [ Ursus arctos (brown bear) ]

Gene ID: 113268927, updated on 15-Mar-2024

Summary

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Gene symbol
ACACA
Gene description
acetyl-CoA carboxylase alpha
See related
EnsemblRapid:ENSUARG00005013114
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus arctos
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
human mouse all
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Genomic context

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See ACACA in Genome Data Viewer
Location:
chromosome: Un
Exon count:
64
Annotation release Status Assembly Chr Location
RS_2023_06 current UrsArc2.0 (GCF_023065955.2) Unplaced Scaffold NW_026622919.1 (34968017..35248402, complement)
102 previous assembly UrsArc1.0 (GCF_023065955.1) Unplaced Scaffold NW_025929507.1 (10547796..10803748)

NW_026622919.1Genomic Context describing neighboring genes Neighboring gene LIM homeobox 1 Neighboring gene apoptosis antagonizing transcription factor Neighboring gene U2 spliceosomal RNA Neighboring gene chromosome unknown C17orf78 homolog Neighboring gene transcriptional adaptor 2A Neighboring gene dual specificity phosphatase 14

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables acetyl-CoA carboxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
acetyl-CoA carboxylase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_023065955.2-RS_2023_06

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UrsArc2.0 Primary Assembly

Genomic

  1. NW_026622919.1 Reference UrsArc2.0 Primary Assembly

    Range
    34968017..35248402 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_057317769.1 → XP_057173752.1  acetyl-CoA carboxylase 1 isoform X3

  2. XM_026517535.4 → XP_026373320.1  acetyl-CoA carboxylase 1 isoform X4

    Conserved Domains (4) summary
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00364
    Location:753 → 818
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1669 → 2217
    Carboxyl_trans; Carboxyl transferase domain
    pfam08326
    Location:820 → 1569
    ACC_central; Acetyl-CoA carboxylase, central region

  3. XM_048223482.2 → XP_048079439.1  acetyl-CoA carboxylase 1 isoform X4

  4. XM_044390787.3 → XP_044246722.1  acetyl-CoA carboxylase 1 isoform X4

    Conserved Domains (4) summary
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00364
    Location:753 → 818
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1669 → 2217
    Carboxyl_trans; Carboxyl transferase domain
    pfam08326
    Location:820 → 1569
    ACC_central; Acetyl-CoA carboxylase, central region

  5. XM_044390790.3 → XP_044246725.1  acetyl-CoA carboxylase 1 isoform X4

    Conserved Domains (4) summary
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00364
    Location:753 → 818
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1669 → 2217
    Carboxyl_trans; Carboxyl transferase domain
    pfam08326
    Location:820 → 1569
    ACC_central; Acetyl-CoA carboxylase, central region

  6. XM_044390785.3 → XP_044246720.1  acetyl-CoA carboxylase 1 isoform X1

    Conserved Domains (3) summary
    cd06850
    Location:792 → 857
    biotinyl_domain; The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase, ...
    COG0439
    Location:157 → 659
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    cl40687
    Location:1693 → 2247
    Carboxyl_trans; Carboxyl transferase domain

  7. XM_057317768.1 → XP_057173751.1  acetyl-CoA carboxylase 1 isoform X2

  8. XM_057317770.1 → XP_057173753.1  acetyl-CoA carboxylase 1 isoform X5

  9. XM_057317771.1 → XP_057173754.1  acetyl-CoA carboxylase 1 isoform X6

  10. XM_026517538.4 → XP_026373323.1  acetyl-CoA carboxylase 1 isoform X4

    Related
    ENSUARP00005021891.1
    Conserved Domains (4) summary
    COG0439
    Location:118 → 620
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00364
    Location:753 → 818
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1669 → 2217
    Carboxyl_trans; Carboxyl transferase domain
    pfam08326
    Location:820 → 1569
    ACC_central; Acetyl-CoA carboxylase, central region

  11. XM_057317772.1 → XP_057173755.1  acetyl-CoA carboxylase 1 isoform X4

  12. XM_026517541.4 → XP_026373326.1  acetyl-CoA carboxylase 1 isoform X10

    Related
    ENSUARP00005022136.1
    Conserved Domains (4) summary
    COG0439
    Location:60 → 562
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    pfam00364
    Location:695 → 760
    Biotin_lipoyl; Biotin-requiring enzyme
    pfam01039
    Location:1611 → 2159
    Carboxyl_trans; Carboxyl transferase domain
    pfam08326
    Location:762 → 1504
    ACC_central; Acetyl-CoA carboxylase, central region

  13. XM_057317773.1 → XP_057173756.1  acetyl-CoA carboxylase 1 isoform X7

  14. XM_044390791.3 → XP_044246726.1  acetyl-CoA carboxylase 1 isoform X8

    Conserved Domains (3) summary
    cd06850
    Location:405 → 470
    biotinyl_domain; The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase, ...
    COG0439
    Location:8 → 272
    AccC; Biotin carboxylase [Lipid transport and metabolism]
    cl40687
    Location:1306 → 1860
    Carboxyl_trans; Carboxyl transferase domain

  15. XM_048223485.2 → XP_048079442.1  acetyl-CoA carboxylase 1 isoform X9

Nucleotide Protein
Heading Accession and Version

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