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STAT5A signal transducer and activator of transcription 5A [ Ursus arctos (brown bear) ]

Gene ID: 113265423, updated on 11-Apr-2024

Summary

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Gene symbol
STAT5A
Gene description
signal transducer and activator of transcription 5A
See related
EnsemblRapid:ENSUARG00005007461
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus arctos
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
human mouse all
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Genomic context

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See STAT5A in Genome Data Viewer
Location:
chromosome: Un
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2023_06 current UrsArc2.0 (GCF_023065955.2) Unplaced Scaffold NW_026622919.1 (19469495..19491710, complement)
102 previous assembly UrsArc1.0 (GCF_023065955.1) Unplaced Scaffold NW_025929507.1 (26292275..26312379)

NW_026622919.1Genomic Context describing neighboring genes Neighboring gene caveolae associated protein 1 Neighboring gene signal transducer and activator of transcription 3 Neighboring gene signal transducer and activator of transcription 5B Neighboring gene GH3 domain containing

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in growth hormone receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to peptide hormone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal transducer and activator of transcription 5A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_023065955.2-RS_2023_06

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UrsArc2.0 Primary Assembly

Genomic

  1. NW_026622919.1 Reference UrsArc2.0 Primary Assembly

    Range
    19469495..19491710 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_057317910.1 → XP_057173893.1  signal transducer and activator of transcription 5A isoform X1

  2. XM_057317911.1 → XP_057173894.1  signal transducer and activator of transcription 5A isoform X1

  3. XM_026512808.4 → XP_026368593.1  signal transducer and activator of transcription 5A isoform X1

    Related
    ENSUARP00005011185.1
    Conserved Domains (4) summary
    cd10421
    Location:573 → 712
    SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:4 → 124
    STAT_int; STAT protein, protein interaction domain

  4. XM_026512809.4 → XP_026368594.1  signal transducer and activator of transcription 5A isoform X2

    Conserved Domains (4) summary
    cd10421
    Location:471 → 610
    SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
    cd16855
    Location:37 → 228
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:230 → 387
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cl03749
    Location:1 → 22
    STAT_int; STAT protein, protein interaction domain

  5. XM_057317912.1 → XP_057173895.1  signal transducer and activator of transcription 5A isoform X2

Nucleotide Protein
Heading Accession and Version

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