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PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [ Ursus arctos (brown bear) ]

Gene ID: 113241143, updated on 15-Mar-2024

Summary

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Gene symbol
PFKFB3
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
See related
EnsemblRapid:ENSUARG00005015385
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus arctos
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
human mouse all
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Genomic context

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See PFKFB3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_06 current UrsArc2.0 (GCF_023065955.2) Unplaced Scaffold NW_026622986.1 (31221654..31297345, complement)
102 previous assembly UrsArc1.0 (GCF_023065955.1) Unplaced Scaffold NW_025929573.1 (28867509..28941895, complement)

NW_026622986.1Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene nucleotide triphosphate diphosphatase NUDT15-like Neighboring gene uncharacterized LOC130542170 Neighboring gene RNA binding motif protein 17 Neighboring gene transfer RNA arginine (anticodon CCU)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_023065955.2-RS_2023_06

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UrsArc2.0 Primary Assembly

Genomic

  1. NW_026622986.1 Reference UrsArc2.0 Primary Assembly

    Range
    31221654..31297345 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044392061.3 → XP_044247996.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X3

    Related
    ENSUARP00005023404.1
    Conserved Domains (1) summary
    PTZ00322
    Location:17 → 431
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

  2. XM_048219458.2 → XP_048075415.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X6

  3. XM_048219457.2 → XP_048075414.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X4

  4. XM_026478720.4 → XP_026334505.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X2

    Related
    ENSUARP00005023679.1
    Conserved Domains (2) summary
    pfam00300
    Location:249 → 435
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase

  5. XM_026478721.4 → XP_026334506.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X5

  6. XM_026478719.4 → XP_026334504.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X1

    Related
    ENSUARP00005023619.1
    Conserved Domains (2) summary
    pfam00300
    Location:249 → 435
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase
Nucleotide Protein
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