U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MIR10526 microRNA 10526 [ Homo sapiens (human) ]

Gene ID: 113218492, updated on 17-Sep-2024

Summary

Official Symbol
MIR10526provided by HGNC
Official Full Name
microRNA 10526provided by HGNC
Primary source
HGNC:HGNC:54016
See related
miRBase:MI0033673; AllianceGenome:HGNC:54016
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See MIR10526 in Genome Data Viewer
Location:
11q24.1
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (122152103..122152156, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (122181094..122181147, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (122022811..122022864, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene mir-100-let-7a-2-mir-125b-1 cluster host gene Neighboring gene BH3-like motif containing, cell death inducer Neighboring gene microRNA let-7a-2 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr11:122050835-122052034 Neighboring gene microRNA 100 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:122067486-122068685 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5665 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5666 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:122100557-122101387 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:122244306-122244840 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4007 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:122292931-122294130 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:122312133-122312797 Neighboring gene RNA, U4atac small nuclear 10, pseudogene

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_162117.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AP001359

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    122152103..122152156 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    122181094..122181147 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)