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DEGS2 delta 4-desaturase, sphingolipid 2 [ Dromaius novaehollandiae (emu) ]

Gene ID: 112989895, updated on 19-Apr-2024

Summary

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Gene symbol
DEGS2
Gene description
delta 4-desaturase, sphingolipid 2
See related
Ensembl:ENSDNVG00000000935
Gene type
protein coding
RefSeq status
MODEL
Organism
Dromaius novaehollandiae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Palaeognathae; Casuariiformes; Dromaiidae; Dromaius
Orthologs
human mouse all
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Genomic context

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See DEGS2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_04 current bDroNov1.hap1 (GCF_036370855.1) 5 NC_088102.1 (14327634..14344923)
100 previous assembly droNov1 (GCF_003342905.1) Unplaced Scaffold NW_020453471.1 (2120210..2137499, complement)

Chromosome 5 - NC_088102.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 29 Neighboring gene YY1 transcription factor Neighboring gene Enah/Vasp-like Neighboring gene EMAP like 1 Neighboring gene uncharacterized LOC112989924

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables sphingolipid delta-4 desaturase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphinganine metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sphingolipid delta(4)-desaturase/C4-monooxygenase DES2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036370855.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bDroNov1.hap1

Genomic

  1. NC_088102.1 Reference bDroNov1.hap1

    Range
    14327634..14344923
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026111293.2 → XP_025967078.1  sphingolipid delta(4)-desaturase/C4-monooxygenase DES2

    UniProtKB/TrEMBL
    A0A7K9B476, A0A8C4IXY1
    Related
    ENSDNVP00000001284.1
    Conserved Domains (2) summary
    cd03508
    Location:26 → 314
    Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...
    pfam08557
    Location:6 → 42
    Lipid_DES; Sphingolipid Delta4-desaturase (DES)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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