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SMAD3 SMAD family member 3 [ Apteryx rowi (Okarito brown kiwi) ]

Gene ID: 112970414, updated on 15-Mar-2024

Summary

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Gene symbol
SMAD3
Gene description
SMAD family member 3
See related
Ensembl:ENSARWG00000004266
Gene type
protein coding
RefSeq status
MODEL
Organism
Apteryx rowi
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Palaeognathae; Apterygiformes; Apterygidae; Apteryx
Orthologs
human mouse all
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Genomic context

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See SMAD3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
100 current aptRow1 (GCF_003343035.1) Unplaced Scaffold NW_020447308.1 (7067478..7142971)

NW_020447308.1Genomic Context describing neighboring genes Neighboring gene lactase like Neighboring gene SMAD family member 6 Neighboring gene alpha and gamma adaptin binding protein Neighboring gene IQ motif containing H

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020447308 Unplaced Scaffold Reference aptRow1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables I-SMAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in SMAD protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in anatomical structure morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transforming growth factor beta receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of heteromeric SMAD protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mothers against decapentaplegic homolog 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Apteryx rowi Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference aptRow1

Genomic

  1. NW_020447308.1 Reference aptRow1

    Range
    7067478..7142971
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026074766.1 → XP_025930551.1  mothers against decapentaplegic homolog 3 isoform X1

    Related
    ENSARWP00000005962.1, ENSARWT00000006851.1
    Conserved Domains (2) summary
    cd10491
    Location:8 → 132
    MH1_SMAD_2_3; N-terminal Mad Homology 1 (MH1) domain in SMAD2 and SMAD3
    cd10985
    Location:225 → 415
    MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3

  2. XM_026074774.1 → XP_025930559.1  mothers against decapentaplegic homolog 3 isoform X2

    Conserved Domains (2) summary
    cd10491
    Location:8 → 132
    MH1_SMAD_2_3; N-terminal Mad Homology 1 (MH1) domain in SMAD2 and SMAD3
    cd10985
    Location:215 → 405
    MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3

  3. XM_026074805.1 → XP_025930590.1  mothers against decapentaplegic homolog 3 isoform X4

    Conserved Domains (2) summary
    cd10985
    Location:120 → 310
    MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3
    cl00055
    Location:1 → 27
    MH1; N-terminal Mad Homology 1 (MH1) domain

  4. XM_026074784.1 → XP_025930569.1  mothers against decapentaplegic homolog 3 isoform X3

    Conserved Domains (2) summary
    cd10985
    Location:163 → 353
    MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3
    cl00055
    Location:7 → 70
    MH1; N-terminal Mad Homology 1 (MH1) domain

  5. XM_026074794.1 → XP_025930579.1  mothers against decapentaplegic homolog 3 isoform X4

    Conserved Domains (2) summary
    cd10985
    Location:120 → 310
    MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3
    cl00055
    Location:1 → 27
    MH1; N-terminal Mad Homology 1 (MH1) domain
Nucleotide Protein
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