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NGLY1 N-glycanase 1 [ Apteryx rowi (Okarito brown kiwi) ]

Gene ID: 112961762, updated on 15-Mar-2024

Summary

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Gene symbol
NGLY1
Gene description
N-glycanase 1
See related
Ensembl:ENSARWG00000013871
Gene type
protein coding
RefSeq status
MODEL
Organism
Apteryx rowi
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Palaeognathae; Apterygiformes; Apterygidae; Apteryx
Orthologs
human mouse all
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Genomic context

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See NGLY1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
16
Annotation release Status Assembly Chr Location
100 current aptRow1 (GCF_003343035.1) Unplaced Scaffold NW_020447619.1 (701731..727952, complement)

NW_020447619.1Genomic Context describing neighboring genes Neighboring gene retinoic acid receptor beta Neighboring gene DNA topoisomerase II beta Neighboring gene uncharacterized LOC112961765 Neighboring gene 3-oxoacyl-ACP synthase, mitochondrial Neighboring gene uncharacterized LOC112961777

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020447619 Unplaced Scaffold Reference aptRow1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycoprotein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein deglycosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein quality control for misfolded or incompletely synthesized proteins IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Apteryx rowi Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference aptRow1

Genomic

  1. NW_020447619.1 Reference aptRow1

    Range
    701731..727952 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026057269.1 → XP_025913054.1  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X2

    Related
    ENSARWP00000020268.1, ENSARWT00000022994.1
    Conserved Domains (4) summary
    cd10459
    Location:43 → 133
    PUB_PNGase; PNGase/UBA or UBX (PUB) domain of the P97 adaptor protein Peptide:N-glycanase (PNGase)
    pfam03835
    Location:358 → 455
    Rad4; Rad4 transglutaminase-like domain
    pfam01841
    Location:295 → 374
    Transglut_core; Transglutaminase-like superfamily
    pfam04721
    Location:477 → 672
    PAW; PNGase C-terminal domain, mannose-binding module PAW

  2. XM_026057270.1 → XP_025913055.1  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X3

    Conserved Domains (3) summary
    cd10459
    Location:43 → 141
    PUB_PNGase; PNGase/UBA or UBX (PUB) domain of the P97 adaptor protein Peptide:N-glycanase (PNGase)
    pfam01841
    Location:303 → 382
    Transglut_core; Transglutaminase-like superfamily
    pfam04721
    Location:448 → 643
    PAW; PNGase C-terminal domain, mannose-binding module PAW

  3. XM_026057271.1 → XP_025913056.1  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X4

    Conserved Domains (4) summary
    cd10459
    Location:43 → 141
    PUB_PNGase; PNGase/UBA or UBX (PUB) domain of the P97 adaptor protein Peptide:N-glycanase (PNGase)
    pfam03835
    Location:366 → 463
    Rad4; Rad4 transglutaminase-like domain
    pfam01841
    Location:303 → 382
    Transglut_core; Transglutaminase-like superfamily
    cl10509
    Location:485 → 617
    PAW; PNGase C-terminal domain, mannose-binding module PAW

  4. XM_026057268.1 → XP_025913053.1  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X1

    Conserved Domains (4) summary
    cd10459
    Location:43 → 141
    PUB_PNGase; PNGase/UBA or UBX (PUB) domain of the P97 adaptor protein Peptide:N-glycanase (PNGase)
    pfam03835
    Location:366 → 463
    Rad4; Rad4 transglutaminase-like domain
    pfam01841
    Location:303 → 382
    Transglut_core; Transglutaminase-like superfamily
    pfam04721
    Location:485 → 680
    PAW; PNGase C-terminal domain, mannose-binding module PAW

  5. XM_026057276.1 → XP_025913061.1  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X5

    Conserved Domains (4) summary
    pfam03835
    Location:257 → 354
    Rad4; Rad4 transglutaminase-like domain
    pfam01841
    Location:194 → 273
    Transglut_core; Transglutaminase-like superfamily
    pfam04721
    Location:376 → 571
    PAW; PNGase C-terminal domain, mannose-binding module PAW
    cl15262
    Location:1 → 32
    PUB; PNGase/UBA or UBX (PUB) domain of p97 adaptor proteins

  6. XM_026057274.1 → XP_025913059.1  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X5

    Conserved Domains (4) summary
    pfam03835
    Location:257 → 354
    Rad4; Rad4 transglutaminase-like domain
    pfam01841
    Location:194 → 273
    Transglut_core; Transglutaminase-like superfamily
    pfam04721
    Location:376 → 571
    PAW; PNGase C-terminal domain, mannose-binding module PAW
    cl15262
    Location:1 → 32
    PUB; PNGase/UBA or UBX (PUB) domain of p97 adaptor proteins

  7. XM_026057273.1 → XP_025913058.1  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X5

    Conserved Domains (4) summary
    pfam03835
    Location:257 → 354
    Rad4; Rad4 transglutaminase-like domain
    pfam01841
    Location:194 → 273
    Transglut_core; Transglutaminase-like superfamily
    pfam04721
    Location:376 → 571
    PAW; PNGase C-terminal domain, mannose-binding module PAW
    cl15262
    Location:1 → 32
    PUB; PNGase/UBA or UBX (PUB) domain of p97 adaptor proteins

  8. XM_026057275.1 → XP_025913060.1  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X5

    Conserved Domains (4) summary
    pfam03835
    Location:257 → 354
    Rad4; Rad4 transglutaminase-like domain
    pfam01841
    Location:194 → 273
    Transglut_core; Transglutaminase-like superfamily
    pfam04721
    Location:376 → 571
    PAW; PNGase C-terminal domain, mannose-binding module PAW
    cl15262
    Location:1 → 32
    PUB; PNGase/UBA or UBX (PUB) domain of p97 adaptor proteins

  9. XM_026057272.1 → XP_025913057.1  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X5

    Conserved Domains (4) summary
    pfam03835
    Location:257 → 354
    Rad4; Rad4 transglutaminase-like domain
    pfam01841
    Location:194 → 273
    Transglut_core; Transglutaminase-like superfamily
    pfam04721
    Location:376 → 571
    PAW; PNGase C-terminal domain, mannose-binding module PAW
    cl15262
    Location:1 → 32
    PUB; PNGase/UBA or UBX (PUB) domain of p97 adaptor proteins

RNA

  1. XR_003252104.1 RNA Sequence

  2. XR_003252105.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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