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TJP2 tight junction protein 2 [ Nothoprocta perdicaria ]

Gene ID: 112944390, updated on 15-Mar-2024

Summary

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Gene symbol
TJP2
Gene description
tight junction protein 2
See related
Ensembl:ENSNPEG00000004719
Gene type
protein coding
RefSeq status
MODEL
Organism
Nothoprocta perdicaria
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Palaeognathae; Tinamiformes; Tinamidae; Nothoprocta
Orthologs
human mouse all
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Genomic context

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See TJP2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
100 current notPer1 (GCF_003342845.1) Unplaced Scaffold NW_020454849.1 (1387925..1450336, complement)

NW_020454849.1Genomic Context describing neighboring genes Neighboring gene amyloid beta precursor protein binding family A member 1 Neighboring gene endosomal transmembrane epsin interactor 1 Neighboring gene phosphatidylinositol-4-phosphate 5-kinase type 1 beta Neighboring gene frataxin

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020454849 Unplaced Scaffold Reference notPer1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nothoprocta perdicaria Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference notPer1

Genomic

  1. NW_020454849.1 Reference notPer1

    Range
    1387925..1450336 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026035817.1 → XP_025891602.1  tight junction protein ZO-2 isoform X1

    UniProtKB/TrEMBL
    A0A8C6YYR9
    Conserved Domains (5) summary
    cd12027
    Location:572 → 634
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:668 → 847
    GuKc; Guanylate kinase homologues
    smart00228
    Location:273 → 351
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl25887
    Location:162 → 261
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  2. XM_026035818.1 → XP_025891603.1  tight junction protein ZO-2 isoform X1

    UniProtKB/TrEMBL
    A0A8C6YYR9
    Conserved Domains (5) summary
    cd12027
    Location:572 → 634
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:668 → 847
    GuKc; Guanylate kinase homologues
    smart00228
    Location:273 → 351
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl25887
    Location:162 → 261
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  3. XM_026035815.1 → XP_025891600.1  tight junction protein ZO-2 isoform X1

    UniProtKB/TrEMBL
    A0A8C6YYR9
    Related
    ENSNPEP00000006249.1, ENSNPET00000006404.1
    Conserved Domains (5) summary
    cd12027
    Location:572 → 634
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:668 → 847
    GuKc; Guanylate kinase homologues
    smart00228
    Location:273 → 351
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl25887
    Location:162 → 261
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  4. XM_026035816.1 → XP_025891601.1  tight junction protein ZO-2 isoform X2

    Conserved Domains (6) summary
    cd12027
    Location:572 → 634
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:668 → 847
    GuKc; Guanylate kinase homologues
    smart00228
    Location:273 → 351
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl25887
    Location:162 → 261
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cl26464
    Location:895 → 1146
    Atrophin-1; Atrophin-1 family

  5. XM_026035819.1 → XP_025891604.1  tight junction protein ZO-2 isoform X3

    Conserved Domains (5) summary
    cd12027
    Location:599 → 661
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:695 → 874
    GuKc; Guanylate kinase homologues
    smart00228
    Location:300 → 378
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl25887
    Location:189 → 288
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
Heading Accession and Version

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