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OCRL OCRL inositol polyphosphate-5-phosphatase [ Vulpes vulpes (red fox) ]

Gene ID: 112934629, updated on 15-Mar-2024

Summary

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Gene symbol
OCRL
Gene description
OCRL inositol polyphosphate-5-phosphatase
See related
Ensembl:ENSVVUG00000008897
Gene type
protein coding
RefSeq status
MODEL
Organism
Vulpes vulpes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes
Orthologs
human mouse all
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Genomic context

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See OCRL in Genome Data Viewer
Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
100 current VulVul2.2 (GCF_003160815.1) Unplaced Scaffold NW_020356581.1 (3642260..3694887)

NW_020356581.1Genomic Context describing neighboring genes Neighboring gene protein Mpv17 pseudogene Neighboring gene SNF2 related chromatin remodeling ATPase 1 Neighboring gene apelin Neighboring gene X-prolyl aminopeptidase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020356581 Unplaced Scaffold Reference VulVul2.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol phosphate phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
inositol polyphosphate 5-phosphatase OCRL-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Vulpes vulpes Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VulVul2.2 Primary Assembly

Genomic

  1. NW_020356581.1 Reference VulVul2.2 Primary Assembly

    Range
    3642260..3694887
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026018104.1 → XP_025873889.1  inositol polyphosphate 5-phosphatase OCRL-1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q7T9V3
    Related
    ENSVVUP00000012041.1, ENSVVUT00000015776.1
    Conserved Domains (3) summary
    cd09093
    Location:239 → 532
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:667 → 897
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
    cd13382
    Location:11 → 115
    PH_OCRL1; oculocerebrorenal syndrome of Lowe 1 Pleckstrin homology-like domain

  2. XM_026018105.1 → XP_025873890.1  inositol polyphosphate 5-phosphatase OCRL-1 isoform X2

    UniProtKB/TrEMBL
    A0A3Q7V2H7
    Conserved Domains (2) summary
    cd09093
    Location:83 → 376
    INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
    cd04380
    Location:511 → 741
    RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
Nucleotide Protein Strain
Heading Accession and Version

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