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TJP2 tight junction protein 2 [ Vulpes vulpes (red fox) ]

Gene ID: 112922121, updated on 15-Mar-2024

Summary

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Gene symbol
TJP2
Gene description
tight junction protein 2
See related
Ensembl:ENSVVUG00000004207
Gene type
protein coding
RefSeq status
MODEL
Organism
Vulpes vulpes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes
Orthologs
human mouse all
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Genomic context

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See TJP2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
100 current VulVul2.2 (GCF_003160815.1) Unplaced Scaffold NW_020356472.1 (9550105..9653952, complement)

NW_020356472.1Genomic Context describing neighboring genes Neighboring gene endosomal transmembrane epsin interactor 1 Neighboring gene DPH3 homolog Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC112922071 Neighboring gene frataxin Neighboring gene uncharacterized LOC112922123

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020356472 Unplaced Scaffold Reference VulVul2.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Vulpes vulpes Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VulVul2.2 Primary Assembly

Genomic

  1. NW_020356472.1 Reference VulVul2.2 Primary Assembly

    Range
    9550105..9653952 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026001574.1 → XP_025857359.1  tight junction protein ZO-2 isoform X6

    UniProtKB/TrEMBL
    A0A3Q7SBF8
    Conserved Domains (5) summary
    cd12027
    Location:668 → 730
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:764 → 943
    GuKc; Guanylate kinase homologues
    cd00992
    Location:91 → 176
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00595
    Location:372 → 446
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cl25887
    Location:213 → 326
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  2. XM_026001569.1 → XP_025857354.1  tight junction protein ZO-2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q7SBF7
    Conserved Domains (5) summary
    cd12027
    Location:668 → 730
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:764 → 943
    GuKc; Guanylate kinase homologues
    smart00228
    Location:368 → 449
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:91 → 176
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl25887
    Location:213 → 326
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  3. XM_026001570.1 → XP_025857355.1  tight junction protein ZO-2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q7TQ95
    Conserved Domains (5) summary
    cd12027
    Location:668 → 730
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:764 → 943
    GuKc; Guanylate kinase homologues
    cd00992
    Location:91 → 176
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00595
    Location:372 → 446
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cl25887
    Location:213 → 326
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  4. XM_026001572.1 → XP_025857357.1  tight junction protein ZO-2 isoform X4

    UniProtKB/TrEMBL
    A0A3Q7T947
    Related
    ENSVVUP00000005371.1, ENSVVUT00000007210.1
    Conserved Domains (5) summary
    cd12027
    Location:609 → 671
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:705 → 884
    GuKc; Guanylate kinase homologues
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00595
    Location:313 → 387
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cl25887
    Location:154 → 267
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  5. XM_026001571.1 → XP_025857356.1  tight junction protein ZO-2 isoform X3

    UniProtKB/TrEMBL
    A0A3Q7SP44
    Related
    ENSVVUP00000005429.1, ENSVVUT00000007290.1
    Conserved Domains (5) summary
    cd12027
    Location:613 → 675
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:709 → 888
    GuKc; Guanylate kinase homologues
    smart00228
    Location:313 → 394
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl25887
    Location:158 → 271
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  6. XM_026001573.1 → XP_025857358.1  tight junction protein ZO-2 isoform X5

    UniProtKB/TrEMBL
    A0A3Q7SLI4
    Conserved Domains (5) summary
    cd12027
    Location:613 → 675
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:709 → 888
    GuKc; Guanylate kinase homologues
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00595
    Location:317 → 391
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cl25887
    Location:158 → 271
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
Nucleotide Protein Strain
Heading Accession and Version

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